DNMT3B 抗体 (AA 1-80)
(2 references)Quick Overview for DNMT3B 抗体 (AA 1-80) (ABIN727623)
抗原
See all DNMT3B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-80
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human Dnmt3 Beta
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亚型
- IgG
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anti-DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B) (AA 1-150) antibody
DNMT3B 适用: 人 IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 7E5E9C1 unconjugated
anti-DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B) (AA 1-150) antibodyDNMT3B 适用: 人 ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 4D1A2E5 unconjugated
anti-DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B) (N-Term) antibodyDNMT3B 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B) (AA 1-100) antibodyDNMT3B 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B) (N-Term) antibodyDNMT3B 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B) (AA 389-417) antibodyDNMT3B 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB01906 unconjugated
anti-DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B) (AA 389-417) antibodyDNMT3B 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B) antibodyDNMT3B 适用: 人 WB, FACS, ICC, DB 宿主: 小鼠 Monoclonal 2280C3a unconjugated
anti-DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B) (AA 1-50) antibodyDNMT3B 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B) (N-Term) antibodyDNMT3B 适用: 人, 猴 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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: "Methylation of Septin9 mediated by DNMT3a enhances hepatic stellate cells activation and liver fibrogenesis." in: Toxicology and applied pharmacology, Vol. 315, pp. 35-49, (2016) (PubMed).
: "Prenatal cocaine exposure impairs cognitive function of progeny via insulin growth factor II epigenetic regulation." in: Neurobiology of disease, Vol. 82, pp. 54-65, (2015) (PubMed).
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: "Methylation of Septin9 mediated by DNMT3a enhances hepatic stellate cells activation and liver fibrogenesis." in: Toxicology and applied pharmacology, Vol. 315, pp. 35-49, (2016) (PubMed).
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- DNMT3B (DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B))
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别名
- Dnmt3 Beta
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背景
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Synonyms: ICF, ICF1, M.HsaIIIB, DNA (cytosine-5)-methyltransferase 3B, Dnmt3b, DNA methyltransferase HsaIIIB, DNA MTase HsaIIIB
Background: Required for genome-wide de novo methylation and is essential for the establishment of DNA methylation patterns during development. DNA methylation is coordinated with methylation of histones. May preferentially methylates nucleosomal DNA within the nucleosome core region. May function as transcriptional co-repressor by associating with CBX4 and independently of DNA methylation. Seems to be involved in gene silencing (By similarity). In association with DNMT1 and via the recruitment of CTCFL/BORIS, involved in activation of BAG1 gene expression by modulating dimethylation of promoter histone H3 at H3K4 and H3K9. Isoforms 4 and 5 are probably not functional due to the deletion of two conserved methyltransferase motifs. Function as transcriptional corepressor by associating with ZHX1.
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基因ID
- 1789
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UniProt
- Q9UBC3
抗原
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