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IL4 Receptor 抗体 (Biotin)

This Biotin-conjugated Human Chimeric anti-IL4 Receptor antibody (Clone DMC284) specifically detects IL4 Receptor in FACS. The antibody is reactive with 人 samples.
产品编号 ABIN7608290
发货至: 中国
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Quick Overview for IL4 Receptor 抗体 (Biotin) (ABIN7608290)

抗原

See all IL4 Receptor (IL4R) 抗体
IL4 Receptor (IL4R) (Interleukin 4 Receptor (IL4R))

适用

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宿主

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Human, 兔

克隆类型

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Chimeric

标记

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This IL4 Receptor antibody is conjugated to Biotin

应用范围

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Flow Cytometry (FACS)

克隆位点

DMC284
  • 原理

    Biotinylated Anti-IL4RA antibody(DMC284), IgG1 Chimeric mAb

    纯化方法

    Purified from cell culture supernatant by affinity chromatography

    亚型

    IgG1
  • 应用备注

    Flow Cyt 1:100

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

    储存条件

    -20 °C,-80 °C

    储存方法

    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

    有效期

    12 months
  • 抗原

    IL4 Receptor (IL4R) (Interleukin 4 Receptor (IL4R))

    别名

    IL4RA

    背景

    This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. Allelic variations in this gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema. Polymorphisms in this gene are also associated with resistance to human immunodeficiency virus type-1 infection. Alternate splicing results in multiple transcript variants.

    UniProt

    P24394

    途径

    JAK/STAT Signaling, Positive Regulation of Immune Effector Process
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