IL21 Receptor 抗体 (Biotin)
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- 抗原 See all IL21 Receptor (IL21R) 抗体
- IL21 Receptor (IL21R) (Interleukin 21 Receptor (IL21R))
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适用
- 人
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宿主
- Human, 兔
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克隆类型
- Chimeric
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标记
- This IL21 Receptor antibody is conjugated to Biotin
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应用范围
- ELISA, Flow Cytometry (FACS)
- 原理
- Biotinylated Anti-IL21R antibody(DMC225), IgG1 Chimeric mAb
- 纯化方法
- Purified from cell culture supernatant by affinity chromatography
- 克隆位点
- DMC225
- 亚型
- IgG1
- Top Product
- Discover our top product IL21R Primary Antibody
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- 应用备注
- ELISA 1:5000-10000, Flow Cyt 1:100
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- IL21 Receptor (IL21R) (Interleukin 21 Receptor (IL21R))
- 别名
- IL21R (IL21R 产品)
- 背景
- The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants have been described.
- UniProt
- Q9HBE5
- 途径
- JAK/STAT Signaling
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