FLT3LG 抗体 (Biotin)
Quick Overview for FLT3LG 抗体 (Biotin) (ABIN7608213)
抗原
See all FLT3LG 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Biotinylated Anti-FLT3LG antibody(DMC421), IgG1 Chimeric mAb
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纯化方法
- Purified from cell culture supernatant by affinity chromatography
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亚型
- IgG1
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anti-Fms-Related tyrosine Kinase 3 Ligand (FLT3LG) (AA 27-189) antibody
FLT3LG 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Fms-Related tyrosine Kinase 3 Ligand (FLT3LG) (AA 27-136) antibodyFLT3LG 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 4C4 unconjugated
anti-Fms-Related tyrosine Kinase 3 Ligand (FLT3LG) (AA 61-160) antibodyFLT3LG 适用: 人, 小鼠 WB, ELISA, ICC, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Fms-Related tyrosine Kinase 3 Ligand (FLT3LG) (AA 83-182) antibodyFLT3LG 适用: 人 WB 宿主: 小鼠 Monoclonal D13 unconjugated
anti-Fms-Related tyrosine Kinase 3 Ligand (FLT3LG) (AA 27-184) antibodyFLT3LG 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Fms-Related tyrosine Kinase 3 Ligand (FLT3LG) (AA 1-235) antibodyFLT3LG 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Fms-Related tyrosine Kinase 3 Ligand (FLT3LG) (C-Term) antibodyFLT3LG 适用: 人, 大鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Fms-Related tyrosine Kinase 3 Ligand (FLT3LG) (AA 27-181) antibodyFLT3LG 适用: 人 WB, IF 宿主: 小鼠 Monoclonal 8D10 unconjugated
anti-Fms-Related tyrosine Kinase 3 Ligand (FLT3LG) (C-Term) antibodyFLT3LG 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Fms-Related tyrosine Kinase 3 Ligand (FLT3LG) antibodyFLT3LG 适用: 人 FACS 宿主: 兔 Chimeric unconjugated Fc fragment
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应用备注
- Flow Cyt 1:100
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
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储存条件
- -20 °C,-80 °C
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储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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有效期
- 12 months
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- FLT3LG (Fms-Related tyrosine Kinase 3 Ligand (FLT3LG))
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别名
- FLT3LG
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背景
- FMS-like tyrosine kinase 3 ligand (Flt-3 Ligand) is also known as FL, Flt3L and FLT3LG, is an a-helical cytokine that promotes the differentiation of multiple hematopoietic cell lineages. FLT3LG is expressed as a noncovalentlylinked dimer by T cells and bone marrow and thymic fibroblasts. Each 36 kDa chain carries approximately 12 kDa of N- and O- linked carbohydrates. FLT3LG is structurally homologous to stem cell factor (SCF) and colony stimulating facor 1 (CSF-1). FLT3LG acts as a growth factor that increases the number of immune cells by activating the hematopoietic progenitors. It also induces the mobilization of the hematopoietic progenitors and stem cells in vivo which may help the system to kill cancer cells. FLT3LG induces the expansion of monocytes and immature dendritic cells as well as early B cell lineage differentiation. FLT3LG cooperates with IL2, IL6, IL7, and IL15 to induce NK cell development and with IL3, IL7 and IL11 to induce terminal B cell maturation. Animal studies also show FLT3LG to reduce the severity of experimentally induced allergic inflammation. FLT3LG is crucial for steady-state pDC and cDC development. A lack of FLT3L results in low levels of DCs.
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UniProt
- P49771
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途径
- RTK signaling
抗原
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