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FLT3 抗体 (Biotin)

This anti-FLT3 antibody is a Human Chimeric antibody detecting FLT3 in FACS. Suitable for 人.
产品编号 ABIN7608212
发货至: 中国

Quick Overview for FLT3 抗体 (Biotin) (ABIN7608212)

抗原

See all FLT3 抗体
FLT3 (Fms-Related tyrosine Kinase 3 (FLT3))

适用

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宿主

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Human, 兔

克隆类型

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Chimeric

标记

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This FLT3 antibody is conjugated to Biotin

应用范围

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Flow Cytometry (FACS)

克隆位点

19A5
  • 原理

    Biotinylated Anti-FLT3 antibody(19A5), IgG1 Chimeric mAb

    纯化方法

    Purified from cell culture supernatant by affinity chromatography

    亚型

    IgG1
  • 应用备注

    Flow Cyt 1/100

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

    储存条件

    -20 °C,-80 °C

    储存方法

    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

    有效期

    12 months
  • 抗原

    FLT3 (Fms-Related tyrosine Kinase 3 (FLT3))

    别名

    FLT3

    背景

    Flt-3(Receptor-type tyrosine-protein kinase FLT3) is also known as FLK-2(Fetal liver kinase-2), STK-1(Stem cell tyrosine kinase 1), CD135. FLT3 is a cytokine receptor which belongs to the receptor tyrosine kinase class III. Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine FLT3LG and regulates differentiation, proliferation and survival of hematopoietic progenitor cells and of dendritic cells. Promotes phosphorylation of SHC1 and AKT1, and activation of the downstream effector MTOR. Promotes activation of RAS signaling and phosphorylation of downstream kinases, including MAPK1/ERK2 and/or MAPK3/ERK1. Mutations that cause constitutive kinase activity promote cell proliferation and resistance to apoptosis via the activation of multiple signaling pathways.

    UniProt

    P36888

    途径

    RTK signaling
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