CD46 抗体 (Biotin)
Quick Overview for CD46 抗体 (Biotin) (ABIN7608119)
抗原
See all CD46 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Biotinylated Anti-CD46 antibody(DM145), Rabbit mAb
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纯化方法
- Purified from cell culture supernatant by affinity chromatography
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亚型
- IgG
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应用备注
- ELISA 1:5000-10000, Flow Cyt 1:100
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
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储存条件
- -20 °C,-80 °C
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储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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有效期
- 12 months
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- CD46
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别名
- CD46
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背景
- The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been described.
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UniProt
- P15529
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途径
- Regulation of Actin Filament Polymerization
抗原
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