SIRT2 抗体
Quick Overview for SIRT2 抗体 (ABIN7606296)
抗原
See all SIRT2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-SIRT2/Sirtuin 2 Rabbit Monoclonal Antibody
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产品特性
- Anti-SIRT2/Sirtuin 2 Rabbit Monoclonal Antibody (ABIN7606296). Tested in WB, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human, Rat.
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纯化方法
- Affinity-chromatography
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免疫原
- A synthesized peptide derived from human SIRT2
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亚型
- IgG
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应用备注
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WB 1:500-1:2000
ICC/IF 1:50-1:200
IP 1:50
FC 1:30 -
限制
- 仅限研究用
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状态
- Liquid
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溶解方式
- Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
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浓度
- Lot specific
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缓冲液
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
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- SIRT2 (Sirtuin 2 (SIRT2))
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别名
- SIRT2
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背景
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Synonyms: NAD-dependent protein deacetylase sirtuin-2,3.5.1.-,Regulatory protein SIR2 homolog 2,SIR2-like protein 2,SIRT2,SIR2L, SIR2L2,
Tissue Specificity: Isoform 1 is expressed in heart, liver and skeletal muscle, weakly expressed in the cortex. Isoform 2 is strongly expressed in the cortex, weakly expressed in heart and liver. Weakly expressed in several malignancies including breast, liver, brain, kidney and prostate cancers compared to normal tissues. Weakly expressed in glioma cell lines compared to normal brain tissues (at protein level). Widely expressed. Highly expressed in heart, brain and skeletal muscle, while it is weakly expressed in placenta and lung. Down-regulated in many gliomas suggesting that it may act as a tumor suppressor gene in human gliomas possibly through the regulation of microtubule network. .
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分子量
- 160-180 kDa
抗原
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