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Menin 抗体

The 兔 单克隆 anti-Menin antibody (Clone ACBA-13) (ABIN7605542) specifically detects Menin in WB, IHC, IP, IF 和 ICC. The antibody is reactive with 人 samples.
产品编号 ABIN7605542
发货至: 中国
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北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Quick Overview for Menin 抗体 (ABIN7605542)

抗原

See all Menin (MEN1) 抗体
Menin (MEN1) (Multiple Endocrine Neoplasia 1 (MEN1))

适用

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宿主

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克隆类型

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单克隆

标记

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This Menin antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF), Immunocytochemistry (ICC)

克隆位点

ACBA-13
  • 原理

    Anti-Menin MEN1 Monoclonal Antibody

    产品特性

    Anti-Menin MEN1 Monoclonal Antibody (ABIN7605542). Tested in WB, IHC, ICC/IF, IP applications. This antibody reacts with Human.

    纯化方法

    Affinity-chromatography

    免疫原

    A synthesized peptide derived from human Menin Menin, the protein product of the MEN1 gene, is a component of the mixed-lineage leukemia protein (MLL) -containing histone methyltransferase complex that facilitates methylation of histone H3 Lys4 to promote transcriptional activation. Menin functions to suppress proliferation of pancreatic islet cells, at least in part through MLL-mediated activation of the p18INK4c (p18) and p27CIP/KIP (p27) cyclin-dependent kinase inhibitor genes.

    亚型

    IgG
  • 应用备注

    WB 1:500-2000
    IHC 1:50-200
    ICC/IF 1:50-200
    IP 1:20

    限制

    仅限研究用
  • 状态

    Liquid

    溶解方式

    Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

    浓度

    0.5 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
  • 抗原

    Menin (MEN1) (Multiple Endocrine Neoplasia 1 (MEN1))

    别名

    MEN1

    背景

    Synonyms: Cytochrome b-245 heavy chain,1.-.-.-,CGD91-phox,Cytochrome b (558) subunit beta,Cytochrome b558 subunit beta,Heme-binding membrane glycoprotein gp91phox,NADPH oxidase 2,Neutrophil cytochrome b 91 kDa polypeptide,Superoxide-generating NADPH oxidase heavy chain subunit,gp91-1,gp91-phox,p22 phagocyte B-cytochrome,CYBB,NOX2,

    Tissue Specificity: Detected in neutrophils (at protein level). .

    分子量

    47 kDa

    UniProt

    O00255

    途径

    Chromatin Binding, Positive Regulation of Endopeptidase Activity
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