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GZMB 抗体

The 兔 单克隆 anti-GZMB antibody is suitable to detect GZMB in samples from 人. It has been validated for IHC, IF, IP 和 ICC.
产品编号 ABIN7605016
发货至: 中国
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Our Local Distributor

中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for GZMB 抗体 (ABIN7605016)

抗原

See all GZMB 抗体
GZMB (Granzyme B (GZMB))

适用

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宿主

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克隆类型

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单克隆

标记

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This GZMB antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC)

克隆位点

AAHC-7
  • 原理

    Anti-Granzyme B GZMB Monoclonal Antibody

    产品特性

    Anti-Granzyme B GZMB Monoclonal Antibody-1. Tested in IHC, ICC/IF, IP applications. This antibody reacts with Human.

    纯化方法

    Affinity-chromatography

    免疫原

    A synthesized peptide derived from human Granzyme B This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.

    亚型

    IgG
  • 应用备注

    IHC 1:50-1:200ICC/IF 1:50-1:200IP 1:50

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    Rabbit IgG in stabilizing components, phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    GZMB (Granzyme B (GZMB))

    别名

    GZMB

    背景

    Granzyme B

    分子量

    23 kDa

    基因ID

    3002

    UniProt

    P10144

    途径

    Apoptosis, Caspase Cascade in Apoptosis
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