MCAM 抗体
Quick Overview for MCAM 抗体 (ABIN7604288)
抗原
See all MCAM 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-CD146 MCAM Rabbit Monoclonal Antibody
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产品特性
- Anti- MCAM Rabbit Monoclonal Antibody (ABIN7604288). Tested in WB, IHC, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.
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纯化方法
- Affinity-chromatography
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免疫原
- A synthesized peptide derived from human CD146
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亚型
- IgG
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应用备注
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WB 1:500-1:2000
IHC 1:50-1:200
ICC/IF 1:50-1:200
IP 1:50
FC 1:50 -
限制
- 仅限研究用
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状态
- Liquid
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溶解方式
- Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
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浓度
- Lot specific
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缓冲液
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
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- MCAM (Melanoma Cell Adhesion Molecule (MCAM))
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别名
- MCAM
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背景
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Synonyms: Cell surface glycoprotein MUC18,Cell surface glycoprotein P1H12,Melanoma cell adhesion molecule,Melanoma-associated antigen A32,Melanoma-associated antigen MUC18,S-endo 1 endothelial-associated antigen,CD146,MCAM,MUC18,
Tissue Specificity: Detected in endothelial cells in vascular tissue throughout the body. May appear at the surface of neural crest cells during their embryonic migration. Appears to be limited to vascular smooth muscle in normal adult tissues. Associated with tumor progression and the development of metastasis in human malignant melanoma. Expressed most strongly on metastatic lesions and advanced primary tumors and is only rarely detected in benign melanocytic nevi and thin primary melanomas with a low probability of metastasis.
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分子量
- 120 kDa
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UniProt
- P43121
抗原
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