Histone H3.3 抗体 (pTyr3)
Quick Overview for Histone H3.3 抗体 (pTyr3) (ABIN7603448)
抗原
See all Histone H3.3 (H3F3A) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- pTyr3
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原理
- Anti-Phospho-Histone H3 (T3) H3F3A Monoclonal Antibody
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产品特性
- Anti-Phospho-Histone H3 (T3) H3F3A Monoclonal Antibody (ABIN7603448). Tested in WB, IHC, ICC/IF, Flow Cytometry applications. This antibody reacts with Human.
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纯化方法
- Affinity-chromatography
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免疫原
- A synthesized peptide derived from human Phospho-Histone H3 (T3) H3 Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
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亚型
- IgG
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应用备注
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WB 1:500-1:2000
IHC 1:50-1:200
ICC/IF 1:50-1:200
FC 1:50 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
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- Histone H3.3 (H3F3A) (H3 Histone, Family 3A (H3F3A))
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别名
- H3F3A
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背景
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Synonyms: Red fluorescent protein eqFP611,GFP-like chromoprotein,
Tissue Specificity: Highly and selectively expressed by undifferentiated rather than differentiated embryonic stem cells (ESC). Levels rapidly diminish as soon as ESC's differentiate (at protein levels). Expressed in almost all epithelial cell membranes but not on mesodermal or neural cell membranes. Found on the surface of adenocarcinoma. .
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分子量
- 15 kDa
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UniProt
- P84243
抗原
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