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SPOP-B 抗体 (N-Term)

The 兔 多克隆 anti-SPOP-B antibody is suitable to detect SPOP-B in samples from 人. It has been validated for WB.
产品编号 ABIN7603237
发货至: 中国
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Quick Overview for SPOP-B 抗体 (N-Term) (ABIN7603237)

抗原

See all SPOP-B 抗体
SPOP-B (Speckle-Type POZ Protein (SPOP-B))

适用

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宿主

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克隆类型

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多克隆

标记

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This SPOP-B antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    N-Term

    原理

    Anti-SPOP Antibody

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-SPOP Antibody (ABIN7603237). Tested in WB applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the N-terminus of human SPOP, identical to the related mouse sequences.

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    SPOP-B (Speckle-Type POZ Protein (SPOP-B))

    别名

    SPOP

    背景

    Synonyms: Tripartite motif-containing protein 6, RING finger protein 89, RING-type E3 ubiquitin transferase TRIM6, TRIM6, RNF89

    Tissue Specificity: Isoform 2 is only expressed in skeletal muscle. Isoform 1 is expressed in skeletal muscle, heart, and in lesser extent in liver or pancreas. .

    Background: Speckle-type POZ protein is a protein that in humans is encoded by the SPOP gene. This gene encodes a protein that may modulate the transcriptional repression activities of death-associated protein 6 (DAXX), which interacts with histone deacetylase, core histones, and other histone-associated proteins. In mouse, the encoded protein binds to the putative leucine zipper domain of macroH2A1.2, a variant H2A histone that is enriched on inactivated X chromosomes. The BTB/POZ domain of this protein has been shown in other proteins to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes. Alternative splicing of this gene results in multiple transcript variants encoding the same protein.

    分子量

    50 kDa

    基因ID

    8405

    UniProt

    O43791
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