Bax Inhibitor 1 抗体 (N-Term)
Quick Overview for Bax Inhibitor 1 抗体 (N-Term) (ABIN7603199)
抗原
See all Bax Inhibitor 1 (TMBIM6) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- Anti-BI-1/TMBIM6 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-BI-1/TMBIM6 Antibody Picoband® (ABIN7603199). Tested in IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human BI-1/TMBIM6, identical to the related mouse and rat sequences.
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亚型
- IgG
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anti-Transmembrane BAX Inhibitor Motif Containing 6 (TMBIM6) antibody
TMBIM6 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal 20F430 unconjugated
anti-Transmembrane BAX Inhibitor Motif Containing 6 (TMBIM6) antibodyTMBIM6 适用: 人, 小鼠, 大鼠 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 20F565 unconjugated
anti-Transmembrane BAX Inhibitor Motif Containing 6 (TMBIM6) antibodyTMBIM6 适用: 人 WB 宿主: 小鼠 Monoclonal 20F248 unconjugated
anti-Transmembrane BAX Inhibitor Motif Containing 6 (TMBIM6) (AA 1-200) antibodyTMBIM6 适用: 人 WB 宿主: 小鼠 Monoclonal ABM20E4 unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Immunofluorescence, 5 μg/mL, Human
1. Bailly-Maitre, B., Fondevila, C., Kaldas, F., Droin, N., Luciano, F., Ricci, J.-E., Croxton, R., Krajewska, M., Zapata, J. M., Kupiec-Weglinski, J. W., Farmer, D., Reed, J. C. Cytoprotective gene bi-1 is required for intrinsic protection from endoplasmic reticulum stress and ischemia-reperfusion injury. Proc. Nat. Acad. Sci. 103: 2809-2814, 2006. 2. Carrara, G., Saraiva, N., Gubser, C., Johnson, B. F., Smith, G. L. Six-transmembrane topology for Golgi anti-apoptotic protein (GAAP) and Bax inhibitor 1 (BI-1) provides model for the transmembrane Bax inhibitor-containing motif (TMBIM) family. J. Biol. Chem. 287: 15896-15905, 2012. 3. Gross, M. B. Personal Communication. Baltimore, Md. 3/22/2016. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- Bax Inhibitor 1 (TMBIM6) (Transmembrane BAX Inhibitor Motif Containing 6 (TMBIM6))
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别名
- TMBIM6
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背景
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Synonyms: Prion-like protein doppel, PrPLP, Prion protein 2, PRND, DPL, UNQ1830/PRO3443
Tissue Specificity: Expressed in testis, in Sertoli cells, ejaculated spermatozoa and in seminal fluid (at protein level).
Background: Bax inhibitor 1 is a protein that in humans is encoded by the TMBIM6 gene. Enables endoribonuclease inhibitor activity and ubiquitin protein ligase binding activity. Involved in several processes, including negative regulation of RNA metabolic process, negative regulation of intrinsic apoptotic signaling pathway, and response to L-glutamate. Acts upstream of or within negative regulation of calcium ion transport into cytosol. Located in endoplasmic reticulum membrane and mitochondrial membrane. Biomarker of cervical squamous cell carcinoma and prostate carcinoma.
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分子量
- 35 kDa
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基因ID
- 7009
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UniProt
- P55061
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途径
- Response to Water Deprivation, ER-Nucleus Signaling
抗原
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