ARID3A 抗体 (N-Term)
Quick Overview for ARID3A 抗体 (N-Term) (ABIN7603197)
抗原
See all ARID3A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- Anti-ARID3A Antibody Picoband®
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交叉反应 (详细)
- No cross-reactivity with other proteins
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产品特性
- Anti-ARID3A Antibody Picoband® (ABIN7603197). Tested in WB, IP, Flow Cytometry applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human ARID3A, which shares 95.8% amino acid (aa) sequence identity with mouse ARID3A.
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亚型
- IgG
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunoprecipitation, 0.5-2 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
1. Alejo-Valle, O., Weigert, K., Bhayadia, R., Ng, M., Issa, H., Beyer, C., Emmrich, S., Schuschel, K., Ihling, C., Sinz, A., Zimmermann, M., Wickenhauser, C., Flasinski, M., Regenyi, E., Labuhn, M., Reinhardt, D., Yaspo, M. L., Heckl, D., Klusmann, J. H. The megakaryocytic transcription factor ARID3A suppresses leukemia pathogenesis. Blood 139: 651-665, 2022. 2. Herrscher, R. F., Kaplan, M. H., Lelsz, D. L., Das, C., Scheuermann, R., Tucker, P. W. The immunoglobulin heavy-chain matrix-associating regions are bound by Bright: a B cell-specific trans-activator that describes a new DNA-binding protein family. Genes Dev. 9: 3067-3082, 1995. 3. Kortschak, R. D., Reimann, H., Zimmer, M., Eyre, H. J., Saint, R., Jenne, D. E. The human dead ringer/bright homolog, DRIL1: cDNA cloning, gene structure, and mapping to D19S886, a marker on 19p13.3 that is strictly linked to the Peutz-Jeghers syndrome. Genomics 51: 288-292, 1998. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- ARID3A (AT Rich Interactive Domain 3A (BRIGHT-Like) (ARID3A))
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别名
- ARID3A
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背景
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Synonyms: ARID3A, DRIL1, DRIL3, DRX, E2FBP1, AT-rich interactive domain-containing protein 3A, ARID domain-containing protein 3A, B-cell regulator of IgH transcription, Bright, Dead ringer-like protein 1, E2F-binding protein 1
Background: AT-rich interactive domain-containing protein 3A is a protein that in humans is encoded by the ARID3A gene. This gene encodes a member of the ARID (AT-rich interaction domain) family of DNA binding proteins. It was found by homology to the Drosophila dead ringer gene, which is important for normal embryogenesis. Other ARID family members have roles in embryonic patterning, cell lineage gene regulation, cell cycle control, transcriptional regulation, and possibly in chromatin structure modification.
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分子量
- 80 kDa
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基因ID
- 1820
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UniProt
- Q99856
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途径
- Chromatin Binding
抗原
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