DUSP1 抗体 (N-Term)
Quick Overview for DUSP1 抗体 (N-Term) (ABIN7603184)
抗原
See all DUSP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- Anti-MKP-1/DUSP1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-MKP-1/DUSP1 Antibody Picoband® (ABIN7603184). Tested in Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human MKP-1/DUSP1, which shares 96.3% amino acid (aa) sequence identity with both mouse and rat MKP-1/DUSP1.
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亚型
- IgG
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anti-Dual Specificity Phosphatase 1 (DUSP1) (C-Term) antibody
Verified DUSP1 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Dual Specificity Phosphatase 1 (DUSP1) (AA 151-250) antibodyDUSP1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Dual Specificity Phosphatase 1 (DUSP1) (AA 305-367) antibodyDUSP1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3A9 unconjugated
anti-Dual Specificity Phosphatase 1 (DUSP1) (AA 305-367) antibodyDUSP1 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 4H7 unconjugated
anti-Dual Specificity Phosphatase 1 (DUSP1) (C-Term) antibodyDUSP1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Dual Specificity Phosphatase 1 (DUSP1) (AA 1-300) antibodyDUSP1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Dual Specificity Phosphatase 1 (DUSP1) (Ser31) antibodyDUSP1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Dual Specificity Phosphatase 1 (DUSP1) (AA 87-101), (C-Term) antibodyDUSP1 适用: 人, 大鼠, 犬 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Dual Specificity Phosphatase 1 (DUSP1) (C-Term) antibodyDUSP1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
1. Alessi, D. R., Smythe, C., Keyse, S. M. The human CL100 gene encodes a tyr/thr-protein phosphatase which potently and specifically inactivates MAP kinase and suppresses its activation by oncogenic ras in Xenopus oocyte extracts. Oncogene 8: 2015-2020, 1993. 2. Bhalla, U. S., Ram, P. T., Iyengar, R. MAP kinase phosphatase as a locus of flexibility in a mitogen-activated protein kinase signaling network. Science 297: 1018-1023, 2002. 3. Brondello, J.-M., Pouyssegur, J., McKenzie, F. R. Reduced MAP kinase phosphatase-1 degradation after p42/p44(MAPK)-dependent phosphorylation. Science 286: 2514-2517, 1999. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- DUSP1 (Dual Specificity Phosphatase 1 (DUSP1))
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别名
- DUSP1
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背景
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Synonyms: Arachidonate 12-lipoxygenase, 12S-type,12S-LOX,12S-lipoxygenase,1.13.11.31,Lipoxin synthase 12-LO,3.3.2.-,Platelet-type lipoxygenase 12,ALOX12,12LO, LOG12,
Tissue Specificity: Expressed in vascular smooth muscle cells. .
Background: Dual specificity protein phosphatase 1 is an enzyme that in humans is encoded by the DUSP1 gene. The protein encoded by this gene is a phosphatase with dual specificity for tyrosine and threonine. The encoded protein can dephosphorylate MAP kinase MAPK1/ERK2, which results in its involvement in several cellular processes. This protein appears to play an important role in the human cellular response to environmental stress as well as in the negative regulation of cellular proliferation. Finally, the encoded protein can make some solid tumors resistant to both chemotherapy and radiotherapy, making it a target for cancer therapy.
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分子量
- 40 kDa
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基因ID
- 1843
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UniProt
- P28562
抗原
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