MAP4K1 抗体 (N-Term)
Quick Overview for MAP4K1 抗体 (N-Term) (ABIN7603180)
抗原
See all MAP4K1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- Anti-MAP4K1/HPK1 Antibody Picoband®
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-MAP4K1/HPK1 Antibody Picoband® (ABIN7603180). Tested in WB applications. This antibody reacts with Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of rat MAP4K1/HPK1, which shares 88.2% and 100% amino acid (aa) sequence identity with human and mouse MAP4K1/HPK1, respectively.
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亚型
- IgG
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应用备注
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Western blot, 0.25-0.5 μg/mL, Rat
1. Hu, M. C.-T., Qiu, W. R., Wang, X., Meyer, C. F., Tan, T.-H. Human HPK1, a novel human hematopoietic progenitor kinase that activates the JNK/SAPK kinase cascade. Genes Dev. 10: 2251-2264, 1996. 2. Kiefer, F., Tibbles, L. A., Anafi, M., Janssen, A., Zanke, B. W., Lassam, N., Pawson, T., Woodgett, J. R., Iscove, N. N. HPK1, a hematopoietic protein kinase activating the SAPK/JNK pathway. EMBO J. 15: 7013-7025, 1996. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- MAP4K1 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 1 (MAP4K1))
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别名
- Map4k1
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背景
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Synonyms: Fascin-2, Retinal fascin, FSCN2
Tissue Specificity: Localized specifically in the outer and inner segments of the photoreceptor cells in the retina.
Background: Mitogen-activated protein kinase kinase kinase kinase 1 is a protein kinase that in humans is encoded by the MAP4K1 gene. It is also known as HPK1 (Hematopoietic Progenitor Kinase 1). The protein has been shown to play a role in JNK activation.
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分子量
- 97 kDa
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基因ID
- 292763
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UniProt
- D3Z8I4
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途径
- TCR Signaling, Signaling of Hepatocyte Growth Factor Receptor
抗原
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