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FOXN1 抗体 (N-Term)

This anti-FOXN1 antibody is a 兔 多克隆 antibody detecting FOXN1 in WB 和 FACS. Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN7603147
发货至: 中国

Quick Overview for FOXN1 抗体 (N-Term) (ABIN7603147)

抗原

See all FOXN1 抗体
FOXN1 (Forkhead Box N1 (FOXN1))

适用

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人, 大鼠, 小鼠

宿主

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克隆类型

  • 45
多克隆

标记

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This FOXN1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Flow Cytometry (FACS)
  • 抗原表位

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    N-Term

    原理

    Anti-FOXN1 Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-FOXN1 Antibody Picoband® (ABIN7603147). Tested in Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the N-terminus of human FOXN1, which shares 85.7% amino acid (aa) sequence identity with mouse FOXN1.

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    1. Adriani, M., Martinez-Mir, A., Fusco, F., Busiello, R., Frank, J., Telese, S., Matrecano, E., Ursini, M. V., Christiano, A. M., Pignata, C. Ancestral founder mutation of the nude (FOXN1) gene in congenital severe combined immunodeficiency associated with alopecia in southern Italy population. Ann. Hum. Genet. 68: 265-268, 2004. 2. Amorosi, S., D'Armiento, M., Calcagno, G., Russo, I., Adriani, M., Christiano, A. M., Weiner, L., Brissette, J. L., Pignata, C. FOXN1 homozygous mutation associated with anencephaly and severe neural tube defect in human athymic Nude/SCID fetus. Clin. Genet. 73: 380-384, 2008. 3. Auricchio, L., Adriani, M., Frank, J., Busiello, R., Christiano, A., Pignata, C. Nail dystrophy associated with a heterozygous mutation of the nude/SCID human FOXN1 (WHN) gene. Arch. Derm. 141: 647-648, 2005.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    FOXN1 (Forkhead Box N1 (FOXN1))

    别名

    FOXN1

    背景

    Synonyms: Vitamin D-binding protein, DBP, VDB, Gc-globulin, Group-specific component, Gc

    Background: The FOXN1 gene encodes a transcription factor that regulates the development of epithelial cells in the thymus and skin. FOXN1 is expressed in thymic epithelial cell precursors which interact with T-cell progenitors for T-cell development in the thymus, and thus plays an essential role in thymic development beginning in the embryo. FOXN1 is also expressed in keratinocytes, hair follicles, epithelial cells in the nail matrix bed, and cells of the choroid plexus.

    分子量

    69 kDa

    基因ID

    8456

    UniProt

    O15353
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