FABP4 抗体 (N-Term)
Quick Overview for FABP4 抗体 (N-Term) (ABIN7603145)
抗原
See all FABP4 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- N-Term
-
原理
- Anti-FABP4 Antibody Picoband® (monoclonal, 10E12)
-
交叉反应 （详细）
- No cross-reactivity with other proteins.
-
产品特性
- Anti-FABP4 Antibody Picoband® (monoclonal, 10E12) (ABIN7603145). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human FABP4, identical to the related mouse and rat sequences.
-
亚型
- IgG1
-
-
anti-Fatty Acid Binding Protein 4, Adipocyte (FABP4) (AA 1-132) antibody
FABP4 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Fatty Acid Binding Protein 4, Adipocyte (FABP4) (AA 2-132) antibodyFABP4 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fatty Acid Binding Protein 4, Adipocyte (FABP4) (AA 2-132) antibodyFABP4 适用: Pig WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fatty Acid Binding Protein 4, Adipocyte (FABP4) (AA 1-132) antibodyFABP4 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 2H3-1G10 unconjugated
anti-Fatty Acid Binding Protein 4, Adipocyte (FABP4) (AA 2-132) antibodyFABP4 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fatty Acid Binding Protein 4, Adipocyte (FABP4) (AA 1-125) antibodyFABP4 适用: 小鸡 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fatty Acid Binding Protein 4, Adipocyte (FABP4) antibodyFABP4 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 小鼠 Monoclonal 1105CT1-1-1 unconjugated
anti-Fatty Acid Binding Protein 4, Adipocyte (FABP4) (AA 2-132) antibodyFABP4 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fatty Acid Binding Protein 4, Adipocyte (FABP4) antibodyFABP4 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Fatty Acid Binding Protein 4, Adipocyte (FABP4) (AA 1-132) antibodyFABP4 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 3G1 unconjugated
-
-
应用备注
-
Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat
1. Hotamisligil, G. S., Johnson, R. S., Distel, R. J., Ellis, R., Papaioannou, V. E., Spiegelman, B. M. : Uncoupling of obesity from insulin resistance through a targeted mutation in aP2, the adipocyte fatty acid binding protein. Science 274: 1377-1379, 1996. 2. Furuhashi, M., Tuncman, G., Gorgun, C. Z., Makowski, L., Atsumi, G., Vaillancourt, E., Kono, K., Babaev, V. R., Fazio, S., Linton, M. F., Sulsky, R., Robl, J. A., Parker, R. A., Hotamisligil, G. S. : Treatment of diabetes and atherosclerosis by inhibiting fatty-acid-binding protein aP2. Nature 447: 959-965, 2007. 3. Shum, B. O. V., Mackay, C. R., Gorgun, C. Z., Frost, M. J., Kumar, R. K., Hotamisligil, G. S., Rolph, M. S. : The adipocyte fatty acid-binding protein aP2 is required in allergic airway inflammation. J. Clin. Invest. 116: 2183-2192, 2006. -
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
-
-
- FABP4 (Fatty Acid Binding Protein 4, Adipocyte (FABP4))
-
别名
- FABP4
-
背景
-
Synonyms: Adhesion molecule antibody, CD31 antibody, CD31 antigen antibody, CD31 EndoCAM antibody, Endocam antibody, FLJ34100 antibody, FLJ58394 antibody, GPIIA antibody, GPIIA' antibody, PECA1 antibody, PECA1_HUMAN antibody, Pecam 1 antibody, PECAM 1 CD31 EndoCAM antibody, PECAM antibody, PECAM-1 antibody, Pecam1 antibody, Platelet endothelial cell adhesion molecule antibody, Platelet/endothelial cell adhesion molecule 1 antibody, Platelet/endothelial cell adhesion molecule antibody
Tissue Specificity: Expressed on platelets and leukocytes and is primarily concentrated at the borders between endothelial cells. Expressed in human umbilical vein endothelial cells (HUVECs) (at protein level). Expressed on neutrophils (at protein level). Isoform Long predominates in all tissues examined. Isoform Delta12 is detected only in trachea. Isoform Delta14-15 is only detected in lung. Isoform Delta14 is detected in all tissues examined with the strongest expression in heart. Isoform Delta15 is expressed in brain, testis, ovary, cell surface of platelets, human umbilical vein endothelial cells (HUVECs), Jurkat T-cell leukemia, human erythroleukemia (HEL) and U-937 histiocytic lymphoma cell lines (at protein level).
Background: Fatty acid binding proteins (FABPs) are small cytoplasmic proteins that are expressed in a highly tissue-specific manner and bind to fatty acids such as oleic and retinoic acid. Adipocyte fatty-acid-binding protein, aP2 (FABP4) is expressed in adipocytes and macrophages, and integrates inflammatory and metabolic responses. Studies in aP2-deficient mice have shown that this lipid chaperone has a significant role in several aspects of metabolic syndrome, including type 2 diabetes and atherosclerosis. It regulates allergic airway inflammation and may provide a link between fatty acid metabolism and asthma.
-
分子量
- 15 kDa
-
基因ID
- 2167
-
UniProt
- P15090
-
途径
- Brown Fat Cell Differentiation
抗原
-
