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SFRP2 抗体 (N-Term)

This anti-SFRP2 antibody is a 兔 多克隆 antibody detecting SFRP2 in WB, IF, ICC 和 FACS. Suitable for 人.
产品编号 ABIN7603133
发货至: 中国

Quick Overview for SFRP2 抗体 (N-Term) (ABIN7603133)

抗原

See all SFRP2 抗体
SFRP2 (Secreted Frizzled-Related Protein 2 (SFRP2))

适用

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宿主

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克隆类型

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多克隆

标记

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This SFRP2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)
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    N-Term

    原理

    Anti-SFRP2 Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-SFRP2 Antibody Picoband® (ABIN7603133). Tested in Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the N-terminus of human SFRP2, identical to the related mouse and rat sequences.

    亚型

    IgG
  • 应用备注

    "Western blot, 0.1-0.25 μg/mL, Human
    Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    "1. Hao XW, et al. Epigenetic inactivation of secreted frizzled-related protein 2 in esophageal squamous cell carcinoma. World J Gastroenterol, 2012 Feb 14. 2. O'Hurley G, et al. The role of secreted frizzled-related protein 2 expression in prostate cancer. Histopathology, 2011 Dec. 3. Sui C, et al. Variation risks of SFRP2 hypermethylation between precancerous disease and colorectal cancer. Tumour Biol, 2014 Oct.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    SFRP2 (Secreted Frizzled-Related Protein 2 (SFRP2))

    别名

    SFRP2

    背景

    Synonyms: Secreted frizzled-related protein 2, FRP-2, sFRP-2, Secreted apoptosis-related protein 1, SARP-1, SFRP2, FRP2, SARP1, FKSG12, UNQ361/PRO697

    Tissue Specificity: Expressed in adipose tissue, heart, brain, skeletal muscle, pancreas, thymus, prostate, testis, ovary, small intestine and colon. Highest levels in adipose tissue, small intestine and colon.

    Background: SFRP2 is also known as FRP-2, SARP1 or SDF-5. It is Expressed in adipose tissue, heart, brain, skeletal muscle, pancreas, thymus, prostate, testis, ovary, small intestine and colon. Highest levels in adipose tissue, small intestine and colon. This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. Methylation of this gene is a potential marker for the presence of colorectal cancer.?

    分子量

    38 kDa

    基因ID

    6423

    途径

    WNT signaling, Tube Formation, Positive Regulation of Endopeptidase Activity, Negative Regulation of intrinsic apoptotic Signaling, Positive Regulation of fat Cell Differentiation
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