SCN11A 抗体 (N-Term)
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- 抗原 See all SCN11A 抗体
- SCN11A (Sodium Channel, Voltage-Gated, Type XI, alpha Subunit (SCN11A))
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抗原表位
- N-Term
- 适用
- 人, 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SCN11A antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), Western Blotting (WB), Flow Cytometry (FACS)
- 原理
- Anti-SCN11A Antibody Picoband®
- 交叉反应 （详细）
- No cross-reactivity with other proteins.
- 产品特性
- Anti-SCN11A Antibody Picoband® (ABIN7603132). Tested in Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
- 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human SCN11A, which shares 87.2% and 89.7% amino acid (aa) sequence identity with mouse and rat SCN11A, respectively.
- 亚型
- IgG
- Top Product
- Discover our top product SCN11A Primary Antibody
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anti-Sodium Channel, Voltage-Gated, Type XI, alpha Subunit (SCN11A) (AA 403-551) antibody
SCN11A 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Sodium Channel, Voltage-Gated, Type XI, alpha Subunit (SCN11A) antibodySCN11A 适用: 人, 大鼠, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sodium Channel, Voltage-Gated, Type XI, alpha Subunit (SCN11A) (AA 1748-1765), (Intracellular) antibodySCN11A 适用: 大鼠 IHC, WB, IF 宿主: 豚鼠 Polyclonal unconjugated
anti-Sodium Channel, Voltage-Gated, Type XI, alpha Subunit (SCN11A) (AA 1726-1791) antibodySCN11A 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 2B10 unconjugated
anti-Sodium Channel, Voltage-Gated, Type XI, alpha Subunit (SCN11A) (Internal Region) antibodySCN11A 适用: 人 ELISA, WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sodium Channel, Voltage-Gated, Type XI, alpha Subunit (SCN11A) (AA 1748-1765), (Intracellular) antibodySCN11A 适用: 大鼠 IHC, WB, IF, IC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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"Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
"1. Dib-Hajj S, Black JA, Cummins TR, Waxman SG (May 2002). "NaN/Nav1.9: a sodium channel with unique properties". Trends in Neurosciences. 25 (5): 253-9. 2. Dib-Hajj SD, Tyrrell L, Waxman SG (2002). "Structure of the sodium channel gene SCN11A: evidence for intron-to-exon conversion model and implications for gene evolution". Molecular Neurobiology. 26 (2-3): 235-50. 3. Dib-Hajj SD, Black JA, Waxman SG (September 2015). "NaV1.9: a sodium channel linked to human pain". Nature Reviews. Neuroscience. 16 (9): 511-9. - 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- 抗原
- SCN11A (Sodium Channel, Voltage-Gated, Type XI, alpha Subunit (SCN11A))
- 别名
- SCN11A (SCN11A 产品)
- 背景
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Synonyms: Sodium channel protein type 11 subunit alpha, Peripheral nerve sodium channel 5, PN5, Sensory neuron sodium channel 2, Sodium channel protein type XI subunit alpha, Voltage-gated sodium channel subunit alpha Nav1.9, hNaN, SCN11A, SCN12A, SNS2
Tissue Specificity: Expressed in the dorsal root ganglia and trigeminal ganglia, olfactory bulb, hippocampus, cerebellar cortex, spinal cord, spleen, small intestine and placenta.
Background: Sodium channel, voltage-gated, type XI, alpha subunit also known as SCN11A or Nav1.9 is a voltage-gated sodium ion channel protein which is encoded by the SCN11A gene on chromosome 3 in humans. Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit with 24 transmembrane domains and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. This gene encodes one member of the sodium channel alpha subunit gene family, and is highly expressed in nociceptive neurons of dorsal root ganglia and trigeminal ganglia. It mediates brain-derived neurotrophic factor-evoked membrane depolarization and is a major effector of peripheral inflammatory pain hypersensitivity. Mutations in this gene have been associated with hereditary sensory and autonomic neuropathy type VII and familial episodic pain syndrome-3. Alternative splicing results in multiple transcript variants.
- 分子量
- 250 kDa
- 基因ID
- 11280
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