MFN1 抗体 (N-Term)
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Quick Overview for MFN1 抗体 (N-Term) (ABIN7603129)
抗原
See all MFN1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- N-Term
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原理
- Anti-Mitofusin 1 MFN1 Antibody (monoclonal, 3H3)
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Mitofusin 1 MFN1 Antibody (monoclonal, 3H3) (ABIN7603129). Tested in IF, ICC, WB applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminal of human Mitofusin 1, different from the related mouse and rat sequences by one amino acid.
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亚型
- IgG2b
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anti-Mitofusin 1 (MFN1) (AA 1-741) antibody
MFN1 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 3C9 unconjugated
anti-Mitofusin 1 (MFN1) (AA 1-234) antibodyMFN1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mitofusin 1 (MFN1) (AA 651-741) antibodyMFN1 适用: 小鼠, 大鼠, 兔, 小鸡 WB, ELISA, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Mitofusin 1 (MFN1) (AA 622-741) antibodyMFN1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Mitofusin 1 (MFN1) (AA 622-741) antibodyMFN1 适用: 人 WB, IHC, ELISA, IP 宿主: 兔 Polyclonal unconjugated
anti-Mitofusin 1 (MFN1) (AA 622-741) antibodyMFN1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Mitofusin 1 (MFN1) (Internal Region) antibodyMFN1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Mitofusin 1 (MFN1) (AA 745-756) antibodyMFN1 适用: 人, 兔, 犬, 马, 猴 IHC, IHC (p) 宿主: 山羊 Polyclonal unconjugated
anti-Mitofusin 1 (MFN1) (AA 209-469) antibodyMFN1 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 4D11 unconjugated
anti-Mitofusin 1 (MFN1) (AA 1-227) antibodyMFN1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- MFN1 (Mitofusin 1 (MFN1))
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别名
- MFN1
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背景
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Synonyms: Fzo homolog antibody|Hfzo1 antibody|Hfzo2 antibody|MFN 1 antibody|Mfn1 antibody|MFN1_HUMAN antibody|Mitochondrial transmembrane GTPase Fzo 1 antibody|Mitochondrial transmembrane GTPase FZO 2 antibody|Mitochondrial transmembrane GTPaseFZO1B antibody|Mitofusin 1 antibody|Mitofusin-1 antibody|Mitofusin1 antibody|Putative transmembrane GTPase antibody|Transmembrane GTPase MFN1 antibody
Tissue Specificity: Ubiquitous.Expressed at slightly higher level in kidney and heart.Isoform 2 may be overexpressed in some tumors,such as lung cancers.
Background: Mitofusin-1 is a protein that in humans is encoded by the MFN1 gene. It is an 80-90 kDa mitochondrial member of the dynamin family of molecules. It is ubiquitously expressed, and found in the outer mitochondrial membrane. The protein encoded by this gene is a mediator of mitochondrial fusion, and thereby contribute to the dynamic balance between fusion and fission that determines mitochondria morphology. MFN1 is known to form oligomers, either with itself or MFN-2, and to undergo ubiquitination by MARCH5. MFN-1 has two key domains. One is a coiled-coil region that mediates MFN-1: MFN-1/2 binding, and a second is a GTPase domain whose cleavage of GTP is necessary for membrane fusion. Overexpression of MFN1 caused perinuclear mitochondrial clustering.
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分子量
- 84 kDa
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基因ID
- 55669
抗原
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