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MFN1 抗体 (N-Term)

This anti-MFN1 antibody is a 小鼠单克隆 antibody detecting MFN1 in WB, ICC 和 IF. Suitable for 人.

产品编号 ABIN7603129

发货至: 中国

Quick Overview for MFN1 抗体 (N-Term) (ABIN7603129)

抗原

See all MFN1 抗体

MFN1 (Mitofusin 1 (MFN1))

适用

53
36
28
21
16
5
4
4
3
2
2
1
1
1

人

宿主

小鼠

克隆类型

单克隆

标记

41
3
3
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1

This MFN1 antibody is un-conjugated

应用范围

57
25
19
17
12
6
6
5
1
1

Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)

克隆位点

3H3

Discover our top product MFN1 Primary Antibody

抗原表位
16

6

6

5

4

3

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1
N-Term

原理

Anti-Mitofusin 1 MFN1 Antibody Picoband® (monoclonal, 3H3)

交叉反应（详细）

No cross-reactivity with other proteins.

产品特性

Anti-Mitofusin 1 MFN1 Antibody Picoband® (monoclonal, 3H3) (ABIN7603129). Tested in IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

纯化方法

Immunogen affinity purified.

免疫原

A synthetic peptide corresponding to a sequence at the N-terminal of human Mitofusin 1, different from the related mouse and rat sequences by one amino acid.

亚型

IgG2b
anti-Mitofusin 1 (MFN1) (AA 1-741) antibody
MFN1 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 3C9 unconjugated

anti-Mitofusin 1 (MFN1) (AA 1-234) antibody
MFN1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Mitofusin 1 (MFN1) (AA 651-741) antibody
MFN1 适用: 小鼠, 大鼠, 兔, 小鸡 WB, ELISA, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Mitofusin 1 (MFN1) (AA 622-741) antibody
MFN1 适用: 人 WB, IHC, ELISA, IP 宿主: 兔 Polyclonal unconjugated

anti-Mitofusin 1 (MFN1) (AA 622-741) antibody
MFN1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Mitofusin 1 (MFN1) (AA 745-756) antibody
MFN1 适用: 人, 兔, 犬, 马, 猴 IHC, IHC (p) 宿主: 山羊 Polyclonal unconjugated

anti-Mitofusin 1 (MFN1) (Internal Region) antibody
MFN1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated

anti-Mitofusin 1 (MFN1) (AA 209-469) antibody
MFN1 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 4D11 unconjugated

anti-Mitofusin 1 (MFN1) (AA 622-741) antibody
MFN1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-Mitofusin 1 (MFN1) (AA 1-227) antibody
MFN1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

应用备注

Western blot, 0.1-0.5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
1. Adams MD, Kerlavage AR, Fields C, Venter JC (Sep 1993). "3,400 new expressed sequence tags identify diversity of transcripts in human brain". Nat Genet 4 (3): 256-67. 2. Meeusen, S., McCaffery, J. M., Nunnari, J. Mitochondrial fusion intermediates revealed in vitro. Science 305: 1747-1752, 2004. 3. Santel, A., Fuller, M. T. Control of mitochondrial morphology by a human mitofusin. J. Cell Sci. 114: 867-874, 2001.

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
抗原

MFN1 (Mitofusin 1 (MFN1))

别名

MFN1

背景

Synonyms: Fzo homolog antibody|Hfzo1 antibody|Hfzo2 antibody|MFN 1 antibody|Mfn1 antibody|MFN1_HUMAN antibody|Mitochondrial transmembrane GTPase Fzo 1 antibody|Mitochondrial transmembrane GTPase FZO 2 antibody|Mitochondrial transmembrane GTPaseFZO1B antibody|Mitofusin 1 antibody|Mitofusin-1 antibody|Mitofusin1 antibody|Putative transmembrane GTPase antibody|Transmembrane GTPase MFN1 antibody
Tissue Specificity: Ubiquitous.Expressed at slightly higher level in kidney and heart.Isoform 2 may be overexpressed in some tumors,such as lung cancers.
Background: Mitofusin-1 is a protein that in humans is encoded by the MFN1 gene. It is an 80-90 kDa mitochondrial member of the dynamin family of molecules. It is ubiquitously expressed, and found in the outer mitochondrial membrane. The protein encoded by this gene is a mediator of mitochondrial fusion, and thereby contribute to the dynamic balance between fusion and fission that determines mitochondria morphology. MFN1 is known to form oligomers, either with itself or MFN-2, and to undergo ubiquitination by MARCH5. MFN-1 has two key domains. One is a coiled-coil region that mediates MFN-1: MFN-1/2 binding, and a second is a GTPase domain whose cleavage of GTP is necessary for membrane fusion. Overexpression of MFN1 caused perinuclear mitochondrial clustering.

分子量

84 kDa

基因ID

55669

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