SH3GL3 抗体 (Middle Region)
Quick Overview for SH3GL3 抗体 (Middle Region) (ABIN7603091)
抗原
See all SH3GL3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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原理
- Anti-SH3GL3 Antibody Picoband®
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-SH3GL3 Antibody Picoband® (ABIN7603091). Tested in Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence in the middle region of human SH3GL3, which shares 95.8% amino acid (aa) sequence identity with mouse and rat SH3GL3.
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亚型
- IgG
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
1. Giachino, C., Lantelme, E., Lanzetti, L., Saccone, S., Della Valle, G., Migone, N. A novel SH3-containing human gene family preferentially expressed in the central nervous system. Genomics 41: 427-434, 1997. 2. Li, S., Qiao, Y., Di, Q., Le, X., Zhang, L., Zhang, X., Zhang, C., Cheng, J., Zong, S., Koide, S. S., Miao, S., Wang, L. Interaction of SH3P13 and DYDC1 protein: a germ cell component that regulates acrosome biogenesis during spermiogenesis. Europ. J. Cell Biol. 88: 509-520, 2009. Note: Erratum: Europ. J. Cell Biol. 98: 51-52, 2019. 3. Petrelli, A., Gilestro, G. F., Lanzardo, S., Comoglio, P. M., Migone, N., Giordano, S. The endophilin-CIN85-Cbl complex mediates ligand-dependent downregulation of c-Met. Nature 416: 187-190, 2002. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- SH3GL3 (Endophilin-A3 (SH3GL3))
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别名
- SH3GL3
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背景
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Synonyms: Interleukin-36 alpha, FIL1 epsilon, Interleukin-1 epsilon, IL-1 epsilon, Interleukin-1 family member 6, IL-1F6, IL36A, FIL1E, IL1E, IL1F6
Tissue Specificity: Expressed in immune system and fetal brain, but not in other tissues tested or in multiple hematopoietic cell lines. Predominantly expressed in skin keratinocytes but not in fibroblasts, endothelial cells or melanocytes. Increased in lesional psoriasis skin.
Background: Endophilin-A3 is a protein that in humans is encoded by the SH3GL3 gene. Enables identical protein binding activity. Predicted to be involved in synaptic vesicle uncoating. Predicted to be located in acrosomal vesicle, early endosome membrane, and presynapse. Predicted to be part of early endosome. Predicted to be active in glutamatergic synapse, postsynaptic density, intracellular component, and postsynaptic endosome.
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分子量
- 42 kDa
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基因ID
- 6457
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UniProt
- Q99963
抗原
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