GZMK 抗体 (Middle Region)
Quick Overview for GZMK 抗体 (Middle Region) (ABIN7603055)
抗原
See all GZMK 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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原理
- Anti-Granzyme K/GZMK Antibody
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Granzyme K/GZMK Antibody Picoband® (ABIN7603055). Tested in IHC applications. This antibody reacts with Human.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence in the middle region of human Granzyme K/GZMK, which shares 71.4% and 73.9% amino acid (aa) sequence identity with mouse and rat GZMK, respectively.
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亚型
- IgG
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anti-Granzyme K (Granzyme 3, Tryptase II) (GZMK) (AA 27-264) antibody
GZMK 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Granzyme K (Granzyme 3, Tryptase II) (GZMK) (Internal Region) antibodyGZMK 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Granzyme K (Granzyme 3, Tryptase II) (GZMK) antibodyGZMK 适用: 人 ELISA, FACS, cELISA 宿主: 小鼠 Monoclonal GM-24C3 unconjugated
anti-Granzyme K (Granzyme 3, Tryptase II) (GZMK) (AA 44-227) antibodyGZMK 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Granzyme K (Granzyme 3, Tryptase II) (GZMK) (AA 61-110) antibodyGZMK 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Granzyme K (Granzyme 3, Tryptase II) (GZMK) antibodyGZMK 适用: 人 ELISA, FACS, cELISA 宿主: 小鼠 Monoclonal GM-26E7 unconjugated
anti-Granzyme K (Granzyme 3, Tryptase II) (GZMK) (Internal Region) antibodyGZMK 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Granzyme K (Granzyme 3, Tryptase II) (GZMK) (AA 87-121) antibodyGZMK 适用: 人 WB 宿主: 兔 Polyclonal RB52998 unconjugated
anti-Granzyme K (Granzyme 3, Tryptase II) (GZMK) (AA 78-127) antibodyGZMK 适用: 人, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Granzyme K (Granzyme 3, Tryptase II) (GZMK) (AA 143-192) antibodyGZMK 适用: 人, Pig WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
1. Baker, E., Sayers, T. J., Sutherland, G. R., Smyth, M. J. The genes encoding NK cell granule serine proteases, human tryptase-2 (TRYP2) and human granzyme A (HFSP), both map to chromosome 5q11-q12 and define a new locus for cytotoxic lymphocyte granule tryptases. Immunogenetics 40: 235-237, 1994. 2. Przetak, M. M., Yoast, S., Schmidt, B. F. Cloning of cDNA for human granzyme 3. FEBS Lett. 364: 268-271, 1995. 3. Sayers, T. J., Lloyd, A. R., McVicar, D. W., O'Connor, M. D., Kelly, J. M., Carter, C. R. D., Wiltrout, T. A., Wiltrout, R. H., Smyth, M. J. Cloning and expression of a second human natural killer cell granule tryptase, HNK-Tryp-2/granzyme 3. J. Leuko. Biol. 59: 763-768, 1996. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- GZMK (Granzyme K (Granzyme 3, Tryptase II) (GZMK))
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别名
- GZMK
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背景
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Synonyms: ELAV-like protein 2, ELAV-like neuronal protein 1, Hu-antigen B, HuB, Nervous system-specific RNA-binding protein Hel-N1, ELAVL2, HUB
Tissue Specificity: Brain, neural-specific.
Background: Granzyme K is a protein that in humans is encoded by the GZMK gene. This gene product is a member of a group of related serine proteases from the cytoplasmic granules of cytotoxic lymphocytes. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here lacks consensus sequences for N-glycosylation present in other granzymes
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分子量
- 41 kDa
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基因ID
- 3003
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UniProt
- P49863
抗原
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