GZMK 抗体 (AA 61-110)
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北京 101111
Quick Overview for GZMK 抗体 (AA 61-110) (ABIN1534448)
抗原
See all GZMK 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 61-110
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原理
- Granzyme K Antibody
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特异性
- Granzyme K Polyclonal Antibody detects endogenous levels of Granzyme K protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human GRAK. AA range:61-110
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- GZMK (Granzyme K (Granzyme 3, Tryptase II) (GZMK))
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背景
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Synonyms: GZMK; TRYP2; Granzyme K; Fragmentin-3; Granzyme-3; NK-tryptase-2; NK-Tryp-2
Background: This gene product is a member of a group of related serine proteases from the cytoplasmic granules of cytotoxic lymphocytes. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here lacks consensus sequences for N-glycosylation present in other granzymes. [provided by RefSeq, Jul 2008],
Gene Name: GZMK
Protein Name: Granzyme K
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分子量
- 28 kDa
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基因ID
- 3003
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OMIM
- 600784
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UniProt
- P49863
抗原
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