GJB2 抗体 (Middle Region)
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北京 101111
Quick Overview for GJB2 抗体 (Middle Region) (ABIN7603054)
抗原
See all GJB2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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原理
- Anti-GJB2 Antibody
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-GJB2 Antibody. Tested in Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence in the middle region of human GJB2, which shares 82.4% amino acid (aa) sequence identity with mouse and rat GJB2.
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亚型
- IgG
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anti-Gap Junction Protein, beta 2, 26kDa (GJB2) (C-Term) antibody
Verified GJB2 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Gap Junction Protein, beta 2, 26kDa (GJB2) (AA 99-131) antibodyGJB2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Gap Junction Protein, beta 2, 26kDa (GJB2) (Cytoplasmic Domain) antibodyGJB2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IHC (p), IHC (fro) 宿主: 小鼠 Monoclonal CX-12H10 unconjugated
anti-Gap Junction Protein, beta 2, 26kDa (GJB2) (AA 1-226) antibodyGJB2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1C6 unconjugated
anti-Gap Junction Protein, beta 2, 26kDa (GJB2) antibodyGJB2 适用: 人, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Gap Junction Protein, beta 2, 26kDa (GJB2) (Internal Region) antibodyGJB2 适用: 人, 小鼠, 大鼠 WB, ICC 宿主: 兔 Polyclonal unconjugated
anti-Gap Junction Protein, beta 2, 26kDa (GJB2) (AA 85-134) antibodyGJB2 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-Gap Junction Protein, beta 2, 26kDa (GJB2) (Internal Region) antibodyGJB2 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Gap Junction Protein, beta 2, 26kDa (GJB2) (N-Term) antibodyGJB2 适用: 人, 犬 WB 宿主: 兔 Polyclonal unconjugated
anti-Gap Junction Protein, beta 2, 26kDa (GJB2) (AA 100-112), (Cytoplasmic Loop), (Intracellular) antibodyGJB2 适用: 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
有效期
- 12 months
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- GJB2 (Gap Junction Protein, beta 2, 26kDa (GJB2))
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别名
- GJB2
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背景
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Background: Connexin26(CX26), also known as GAP junction protein, beta2, GJB2. Gap junctions were first characterized by electron microscopy as regionally specialized structures on plasma membranes of contacting adherent cells. These structures were shown to consist of cell-to-cell channels. Proteins, called connexins, purified from fractions of enriched gap junctions from different tissues differ. The 3-prime untranslated region of the CX26 transcript contains a putative mRNA instability sequence. The deduced 226-amino acid protein has a calculated molecular mass of about 26 kD. CX26 shares 92.5 % identity with rat Cx26. connexin 26(GJB2) is assigned to human chromosome 13q11-q12 .Connexin 26 regulates epidermal barrier and wound remodeling and promotes psoriasiform response. Connexin 26 gene(GJB2) mutation modulates the severity of hearing loss associated with the 1555A-G mitochondrial mutation.
Gene Full Name: gap junction protein beta 2
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分子量
- 26 kDa
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基因ID
- 2706
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UniProt
- P29033
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途径
- Sensory Perception of Sound, Cell-Cell Junction Organization
抗原
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