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ALOX5AP 抗体 (Middle Region)

ALOX5AP 适用: 人 WB, FACS, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7603016
发货至: 中国
  • 抗原 See all ALOX5AP 抗体
    ALOX5AP (Arachidonate 5-Lipoxygenase-Activating Protein (ALOX5AP))
    抗原表位
    • 3
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 9
    • 2
    • 1
    宿主
    • 7
    • 3
    克隆类型
    • 8
    • 2
    多克隆
    标记
    • 9
    • 1
    This ALOX5AP antibody is un-conjugated
    应用范围
    • 9
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunocytochemistry (ICC)
    原理
    Anti-ALOX5AP Antibody Picoband®
    交叉反应 (详细)
    No cross-reactivity with other proteins
    产品特性
    Anti-ALOX5AP Antibody Picoband® (ABIN7603016). Tested in WB, ICC/IF, Flow Cytometry applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence in the middle region of human ALOX5AP, identical to the related mouse and rat sequences.
    亚型
    IgG
    Top Product
    Discover our top product ALOX5AP Primary Antibody
  • 应用备注
    Western blot, 0.25-0.5 μg/mL, Human
    Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    1. Dixon, R. A. F., Diehl, R. E., Opas, E., Rands, E., Vickers, P. J., Evans, J. F., Gillard, J. W., Miller, D. K. Requirement of a 5-lipoxygenase-activating protein for leukotriene synthesis. Nature 343: 282-284, 1990. 2. Ferguson, A. D., McKeever, B. M., Xu, S., Wisniewski, D., Miller, D. K., Yamin, T.-T., Spencer, R. H., Chu, L., Ujjainwalla, F., Cunningham, B. R., Evans, J. F., Becker, J. W. Crystal structure of inhibitor-bound human 5-lipoxygenase-activating protein. Science 317: 510-512, 2007. 3. Kennedy, B. P., Diehl, R. E., Boie, Y., Adam, M., Dixon, R. A. F. Gene characterization and promoter analysis of the human 5-lipoxygenase-activating protein (FLAP). J. Biol. Chem. 266: 8511-8516, 1991.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
    储存条件
    4 °C,-20 °C
    储存方法
    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原
    ALOX5AP (Arachidonate 5-Lipoxygenase-Activating Protein (ALOX5AP))
    别名
    ALOX5AP (ALOX5AP 产品)
    背景

    Synonyms: ALOX5AP, FLAP, Arachidonate 5-lipoxygenase-activating protein, FLAP, MK-886-binding protein

    Background: This gene encodes a protein which, with 5-lipoxygenase, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the plasma membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit 5-lipoxygenase activation. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

    分子量
    18 kDa
    基因ID
    241
    UniProt
    P20292
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