YY1 抗体 (Middle Region)
Quick Overview for YY1 抗体 (Middle Region) (ABIN7603001)
抗原
See all YY1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- Middle Region
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原理
- Anti-YY1 Antibody Picoband® (monoclonal, 6H3E1)
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-YY1 Antibody Picoband® (monoclonal, 6H3E1) (ABIN7603001). Tested in Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence in the middle region of human YY1, identical to the related mouse sequence.
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亚型
- IgG2b
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
1. Shi Y, Seto E, Chang LS, Shenk T (Oct 1991). "Transcriptional repression by YY1, a human GLI-Krüppel-related protein, and relief of repression by adenovirus E1A protein". Cell 67 (2): 377-88. 2. Thiaville MM, Kim J (2011). "Oncogenic potential of yin yang 1 mediated through control of imprinted genes". Critical Reviews in Oncogenesis 16 (3-4): 199-209. 3. Zhu W, Lossie AC, Camper SA, Gumucio DL (Apr 1994). "Chromosomal localization of the transcription factor YY1 in the mouse and human". Mammalian Genome 5 (4): 234-6. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- YY1 (YY1 Transcription Factor (YY1))
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别名
- YY1
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背景
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Synonyms: Dihydrofolate reductase, DHFR
Tissue Specificity: Widely expressed in fetal and adult tissues, including throughout the fetal and adult brains and whole blood. Expression is higher in the adult brain than in the fetal brain.
Background: YY1 (Yin Yang 1) is a transcriptional repressor protein in humans that is encoded by the YY1 gene. YY1 is a ubiquitously distributed transcription factor belonging to the GLI-Kruppel class of zinc finger proteins. The protein is involved in repressing and activating a diverse number of promoters. YY1 may histone deacetylases and histone acetyltransferases to a promoter in order to activate or repress the promoter, thus implicating histone modification in the function of YY1.
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分子量
- 65 kDa
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基因ID
- 7528
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UniProt
- P25490
抗原
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