Annexin A3 抗体 (Middle Region)
Quick Overview for Annexin A3 抗体 (Middle Region) (ABIN7602989)
抗原
See all Annexin A3 (ANXA3) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- Middle Region
-
原理
- Anti-Annexin A3 Antibody Picoband® (monoclonal, 2H3H8)
-
交叉反应 （详细）
- No cross-reactivity with other proteins.
-
产品特性
- Anti-Annexin A3 Antibody Picoband® (monoclonal, 2H3H8) (ABIN7602989). Tested in Flow Cytometry, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- A synthetic peptide corresponding to a sequence in the middle region of human Annexin A3, different from the related mouse sequence by one amino acid, and from the related rat sequence by three amino acids.
-
亚型
- IgG2b
-
-
anti-Annexin A3 (ANXA3) (AA 1-323) antibody
ANXA3 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Annexin A3 (ANXA3) (AA 26-160) antibodyANXA3 适用: 人 WB, ELISA, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Annexin A3 (ANXA3) antibodyANXA3 适用: 人, 大鼠 WB, IHC, IHC (p), FACS 宿主: 小鼠 Monoclonal 1A5 unconjugated
anti-Annexin A3 (ANXA3) (AA 1-323) antibodyANXA3 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 4F1 unconjugated
anti-Annexin A3 (ANXA3) (AA 153-184), (Middle Region) antibodyANXA3 适用: 人, 小鼠, 大鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Annexin A3 (ANXA3) (AA 1-323) antibodyANXA3 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 1E2 unconjugated
anti-Annexin A3 (ANXA3) (AA 190-312) antibodyANXA3 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C4 unconjugated
anti-Annexin A3 (ANXA3) antibodyANXA3 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Annexin A3 (ANXA3) (AA 19-154) antibodyANXA3 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Annexin A3 (ANXA3) (N-Term) antibodyANXA3 适用: 人, 兔, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
1. Bianchi C, et al. Primary cell cultures from human renal cortex and renal-cell carcinoma evidence a differential expression of two spliced isoforms of Annexin A3. Am J Pathol, 2010 Apr. 2. Jung EJ, et al. Decreased annexin A3 expression correlates with tumor progression in papillary thyroid cancer. Proteomics Clin Appl, 2010 May. 3. Yan X, et al. Increased expression of annexin A3 is a mechanism of platinum resistance in ovarian cancer. Cancer Res, 2010 Feb 15. -
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
-
-
- Annexin A3 (ANXA3)
-
别名
- ANXA3
-
背景
-
Synonyms: Cofilin-2, Cofilin, muscle isoform, CFL2
Tissue Specificity: Isoform CFL2b is expressed predominantly in skeletal muscle and heart. Isoform CFL2a is expressed in various tissues.
Background: Annexin A3 is a protein that in humans is encoded by the Annexin A3 gene. The Annexin A3 gene contains 13 exons and spans 58 kb of genomic DNA. The Annexin A3 gene is mapped to 4q21. It is abnormally expressed in fetuses of both IVF and ICSI, which may contribute to the increase risk of birth defects in these ART. This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions in the inhibition of phospholipase A2 and cleavage of inositol 1,2-cyclic phosphate to form inositol 1-phosphate. This protein may also play a role in anti-coagulation.
-
分子量
- 36 kDa
-
基因ID
- 306
-
UniProt
- P12429
抗原
-
