RENT1/UPF1 抗体 (Middle Region)
Quick Overview for RENT1/UPF1 抗体 (Middle Region) (ABIN7602979)
抗原
See all RENT1/UPF1 (UPF1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- Middle Region
-
原理
- Anti-RENT1/hUPF1 Antibody Picoband® (monoclonal, 11E7)
-
交叉反应 （详细）
- No cross-reactivity with other proteins.
-
产品特性
- Anti-RENT1/hUPF1 Antibody Picoband® (monoclonal, 11E7) (ABIN7602979). Tested in IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- A synthetic peptide corresponding to a sequence in the middle region of human RENT1/hUPF1, identical to the related mouse and rat sequences.
-
亚型
- IgG2b
-
-
anti-UPF1 Regulator of Nonsense Transcripts Homolog (UPF1) (AA 270-370) antibody
UPF1 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-UPF1 Regulator of Nonsense Transcripts Homolog (UPF1) (AA 270-370) antibodyUPF1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-UPF1 Regulator of Nonsense Transcripts Homolog (UPF1) antibodyUPF1 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-UPF1 Regulator of Nonsense Transcripts Homolog (UPF1) antibodyUPF1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-UPF1 Regulator of Nonsense Transcripts Homolog (UPF1) (AA 578-614), (Middle Region) antibodyUPF1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-UPF1 Regulator of Nonsense Transcripts Homolog (UPF1) (AA 301-450) antibodyUPF1 适用: 人 ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-UPF1 Regulator of Nonsense Transcripts Homolog (UPF1) (AA 583-612) antibodyUPF1 适用: 人 WB 宿主: 兔 Polyclonal RB8354 unconjugated
anti-UPF1 Regulator of Nonsense Transcripts Homolog (UPF1) (AA 1019-1116) antibodyUPF1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4G3 unconjugated
anti-UPF1 Regulator of Nonsense Transcripts Homolog (UPF1) (AA 956-1125) antibodyUPF1 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-UPF1 Regulator of Nonsense Transcripts Homolog (UPF1) (AA 1019-1116) antibodyUPF1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4G3 unconjugated
-
-
应用备注
-
Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
1. "Entrez Gene: UPF1 UPF1 regulator of nonsense transcripts homolog (yeast)". 2. Applequist SE, Selg M, Raman C, Jack HM (March 1997). "Cloning and characterization of HUPF1, a human homolog of the Saccharomyces cerevisiae nonsense mRNA-reducing UPF1 protein". Nucleic Acids Res 25 (4): 814-21. 3. Perlick HA, Medghalchi SM, Spencer FA, Kendzior RJ Jr, Dietz HC (November 1996). "Mammalian orthologues of a yeast regulator of nonsense transcript stability". Proc Natl Acad Sci U S A 93 (20): 10928-32. -
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
-
-
- RENT1/UPF1 (UPF1) (UPF1 Regulator of Nonsense Transcripts Homolog (UPF1))
-
别名
- UPF1
-
背景
-
Synonyms: ATP dependent helicase RENT1 antibody, ATP-dependent helicase RENT1 antibody, Delta helicase antibody, FLJ43809 antibody, FLJ46894 antibody, HUPF 1 antibody, hUpf1 antibody, KIAA0221 antibody, Nonsense mRNA reducing factor 1 antibody, NORF 1 antibody, NORF1 antibody, pNORF 1 antibody, pNORF1 antibody, Regulator of nonsense transcripts 1 antibody, RENT 1 antibody, RENT1 antibody, RENT1_HUMAN antibody, Smg 2 antibody, Smg 2 homolog nonsense mediated mRNA decay factor antibody, UP Frameshift 1 antibody, Up frameshift mutation 1 homolog (S. cerevisiae) antibody, Up frameshift mutation 1 homolog antibody, Up frameshift suppressor 1 homolog antibody, Up-frameshift suppressor 1 homolog antibody, UPF 1 antibody, UPF 1 regulator of nonsense transcripts homolog antibody, upf1 antibody, UPF1 regulator of nonsense transcripts homolog antibody, Yeast Upf1p homolog antibody
Tissue Specificity: Ubiquitous.
Background: Regulator of nonsense transcripts 1 is a protein that in humans is encoded by the UPF1 gene. This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. And this protein is located only in the cytoplasm. When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping. Use of multiple polyadenylation sites has been noted for this gene. Alternative splicing results in multiple transcript variants.
-
分子量
- 130 kDa
-
基因ID
- 5976
-
UniProt
- Q92900
-
途径
- SARS-CoV-2 Protein Interactome
抗原
-
