SMAD5 抗体 (Middle Region)
Quick Overview for SMAD5 抗体 (Middle Region) (ABIN7602972)
抗原
See all SMAD5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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原理
- Anti-SMAD5 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-SMAD5 Antibody Picoband® (ABIN7602972). Tested in WB applications. This antibody reacts with Human, Monkey, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence in the middle region of human SMAD5, which shares 95.5% amino acid (aa) sequence identity with both mouse and rat SMAD5.
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亚型
- IgG
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anti-SMAD, Mothers Against DPP Homolog 5 (SMAD5) (AA 210-464) antibody
SMAD5 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-SMAD, Mothers Against DPP Homolog 5 (SMAD5) (AA 140-240) antibodySMAD5 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-SMAD, Mothers Against DPP Homolog 5 (SMAD5) antibodySMAD5 适用: 人, 大鼠 WB, ELISA, IHC, ICC, FACS 宿主: 小鼠 Monoclonal 3H9 unconjugated
anti-SMAD, Mothers Against DPP Homolog 5 (SMAD5) (AA 1-209) antibodySMAD5 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-SMAD, Mothers Against DPP Homolog 5 (SMAD5) (AA 105-182) antibodySMAD5 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3A10 unconjugated
anti-SMAD, Mothers Against DPP Homolog 5 (SMAD5) (AA 186-465) antibodySMAD5 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-SMAD, Mothers Against DPP Homolog 5 (SMAD5) (pSer463), (pSer465) antibodySMAD5 适用: 人, 小鼠, 大鼠 WB, IF (cc), IHC (p) 宿主: 兔 Monoclonal 1B8 unconjugated
anti-SMAD, Mothers Against DPP Homolog 5 (SMAD5) (AA 105-182) antibodySMAD5 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 5E12 unconjugated
anti-SMAD, Mothers Against DPP Homolog 5 (SMAD5) antibodySMAD5 适用: 人 WB, IP 宿主: 兔 Monoclonal unconjugated
anti-SMAD, Mothers Against DPP Homolog 5 (SMAD5) (AA 248-267), (Middle Region) antibodySMAD5 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Monkey, Mouse, Rat
1. Bruno, E., Horrigan, S. K., Van Den Berg, D., Rozler, E., Fitting, P. R., Moss, S. T., Westbrook, C., Hoffman, R. The Smad5 gene is involved in the intracellular signaling pathways that mediate the inhibitory effects of transforming growth factor-beta on human hematopoiesis. Blood 91: 1917-1923, 1998. 2. Davis, B. N., Hilyard, A. C., Lagna, G., Hata, A. SMAD proteins control DROSHA-mediated microRNA maturation. Nature 454: 56-61, 2008. 3. Gemma, A., Hagiwara, K., Vincent, F., Ke, Y., Hancock, A. R., Nagashima, M., Bennett, W. P., Harris, C. C. hSmad5 gene, a human hSmad family member: its full length cDNA, genomic structure, promoter region and mutation analysis in human tumors. Oncogene 16: 951-956, 1998. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- SMAD5 (SMAD, Mothers Against DPP Homolog 5 (SMAD5))
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别名
- SMAD5
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背景
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Synonyms: Mothers against decapentaplegic homolog 5, MAD homolog 5, Mothers against DPP homolog 5, JV5-1, SMAD family member 5, SMAD 5, Smad5, hSmad5, SMAD5, MADH5
Tissue Specificity: Ubiquitous.
Background: Mothers against decapentaplegic homolog 5 also known as SMAD5 is a protein that in humans is encoded by the SMAD5 gene. It is mapped to 5q31.1. The protein encoded by this gene is involved in the transforming growth factor beta signaling pathway that results in an inhibition of the proliferation of hematopoietic progenitor cells. The encoded protein is activated by bone morphogenetic proteins type 1 receptor kinase, and may be involved in cancer. Alternative splicing results in multiple transcript variants.
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分子量
- 52 kDa
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基因ID
- 4090
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UniProt
- Q99717
抗原
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