Presenilin 1 抗体 (Catalytic Subunit)
Quick Overview for Presenilin 1 抗体 (Catalytic Subunit) (ABIN7602951)
抗原
See all Presenilin 1 (PSEN1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- Catalytic Subunit
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原理
- Anti-Presenilin 1 Monoclonal Antibody
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产品特性
- Anti-Presenilin 1 Monoclonal Antibody (ABIN7602951). Tested in WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.
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纯化方法
- Affinity-chromatography
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免疫原
- A synthesized peptide derived from human Presenilin 1 Probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein) . Requires the other members of the gamma-secretase complex to have a protease activity.
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亚型
- IgG
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应用备注
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WB 1:500-1:2000
FC 1:10 -
限制
- 仅限研究用
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状态
- Liquid
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溶解方式
- Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
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浓度
- Lot specific
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缓冲液
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
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- Presenilin 1 (PSEN1)
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别名
- PSEN1
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背景
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Synonyms: Monocyte differentiation antigen CD14 ,Myeloid cell-specific leucine-rich glycoprotein,CD14,Monocyte differentiation antigen CD14, urinary form,Monocyte differentiation antigen CD14, membrane-bound form,CD14,
Tissue Specificity: Detected on macrophages (at protein level) (PubMed:1698311). Expressed strongly on the surface of monocytes and weakly on the surface of granulocytes, also expressed by most tissue macrophages. .
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分子量
- 25 kDa
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UniProt
- P49768
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途径
- Notch Signaling, EGFR Signaling Pathway, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
抗原
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