WIPF1 抗体 (C-Term)
Quick Overview for WIPF1 抗体 (C-Term) (ABIN7602942)
抗原
See all WIPF1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- Anti-WIPF1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-WIPF1 Antibody Picoband® (ABIN7602942). Tested in Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human WIPF1, which shares 95% amino acid (aa) sequence identity with mouse and rat WIPF1.
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亚型
- IgG
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anti-WAS/WASL Interacting Protein Family, Member 1 (WIPF1) (AA 400-500) antibody
WIPF1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-WAS/WASL Interacting Protein Family, Member 1 (WIPF1) (C-Term) antibodyWIPF1 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-WAS/WASL Interacting Protein Family, Member 1 (WIPF1) (C-Term) antibodyWIPF1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-WAS/WASL Interacting Protein Family, Member 1 (WIPF1) (N-Term) antibodyWIPF1 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
1. Al-Mousa, H., Hawwari, A., Al-Ghonaium, A., Al-Saud, B., Al-Dhekri, H., Al-Muhsen, S., Elshorbagi, S., Dasouki, M., El-Baik, L., Alseraihy, A., Ayas, M., Arnaout, R. Hematopoietic stem cell transplantation corrects WIP deficiency. (Letter) J. Allergy Clin. Immun. 139: 1039-1040, 2017. 2. Anton, I. M., de la Fuente, M. A., Sims, T. N., Freeman, S., Ramesh, N., Hartwig, J. H., Dustin, M. L., Geha, R. S. WIP deficiency reveals a differential role for WIP and the actin cytoskeleton in T and B cell activation. Immunity 16: 193-204, 2002. 3. Gross, M. B. Personal Communication. Baltimore, Md. 2/23/2012. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- WIPF1 (WAS/WASL Interacting Protein Family, Member 1 (WIPF1))
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别名
- WIPF1
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背景
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Synonyms: Vascular endothelial growth factor B, VEGF-B, VEGF-related factor, VRF, VEGFB, VRF
Tissue Specificity: Expressed in all tissues except liver. Highest levels found in heart, skeletal muscle and pancreas.
Background: WAS/WASL-interacting protein (WIP) is a protein that in humans is encoded by the WIPF1 gene. This gene encodes a protein that plays an important role in the organization of the actin cytoskeleton. The encoded protein binds to a region of Wiskott-Aldrich syndrome protein that is frequently mutated in Wiskott-Aldrich syndrome, an X-linked recessive disorder. Impairment of the interaction between these two proteins may contribute to the disease. Two transcript variants encoding the same protein have been identified for this gene.
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分子量
- 56 kDa
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基因ID
- 7456
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UniProt
- O43516
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途径
- RTK signaling
抗原
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