TLR9 抗体 (C-Term)
Quick Overview for TLR9 抗体 (C-Term) (ABIN7602935)
抗原
See all TLR9 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- Anti-TLR9 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-TLR9 Antibody Picoband® (ABIN7602935). Tested in IHC, WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human TLR9, which shares 97.1% amino acid (aa) sequence identity with mouse TLR9.
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亚型
- IgG
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anti-Toll-Like Receptor 9 (TLR9) (AA 868-1016) antibody
TLR9 适用: 人 IHC, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 1B12H2 unconjugated
anti-Toll-Like Receptor 9 (TLR9) (AA 28-362) antibodyTLR9 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 9 (TLR9) (AA 350-450) antibodyTLR9 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 9 (TLR9) (AA 26-193) antibodyTLR9 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 5B10E8 unconjugated
anti-Toll-Like Receptor 9 (TLR9) (AA 951-1032) antibodyTLR9 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (p), IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 9 (TLR9) (AA 99-215) antibodyTLR9 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1E8 unconjugated
anti-Toll-Like Receptor 9 (TLR9) (N-Term) antibodyTLR9 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 9 (TLR9) antibodyTLR9 适用: 人 WB, FACS, IHC (p), IF 宿主: 小鼠 Monoclonal 5G5 unconjugated
anti-Toll-Like Receptor 9 (TLR9) antibody (FITC)TLR9 适用: 人 WB, FACS, IHC (p), IF 宿主: 小鼠 Monoclonal 5G5 FITC
anti-Toll-Like Receptor 9 (TLR9) (AA 26-332) antibodyTLR9 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Rat
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
1. Asagiri, M., Hirai, T., Kunigami, T., Kamano, S., Gober, H.-J., Okamoto, K., Nishikawa, K., Latz, E., Golenbock, D. T., Aoki, K., Ohya, K., Imai, Y., Morishita, Y., Miyazono, K., Kato, S., Saftig, P., Takayanagi, H. Cathepsin K-dependent Toll-like receptor 9 signaling revealed in experimental arthritis. Science 319: 624-627, 2008. 2. Babiuk, S., Mookherjee, N., Pontarollo, R., Griebel, P., van Drunen Littel-van den Hurk, S., Hecker, R., Babiuk, L. TLR9-/- and TLR9+/+ mice display similar immune responses to a DNA vaccine. Immunology 113: 114-120, 2004. 3. Baumann, C. L., Aspalter, I. M., Sharif, O., Pichlmair, A., Bluml, S., Grebien, F., Bruckner, M., Pasierbek, P., Aumayr, K., Planyavsky, M., Bennett, K. L., Colinge, J., Knapp, S., Superti-Furga, G. CD14 is a coreceptor of Toll-like receptors 7 and 9. J. Exp. Med. 207: 2689-2701, 2010. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- TLR9 (Toll-Like Receptor 9 (TLR9))
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别名
- TLR9
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背景
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Synonyms: Toll-like receptor 3, CD283, TLR3
Tissue Specificity: Expressed at high level in placenta and pancreas. Also detected in CD11c+ immature dendritic cells. Only expressed in dendritic cells and not in other leukocytes, including monocyte precursors. TLR3 is the TLR that is expressed most strongly in the brain, especially in astrocytes, glia, and neurons.
Background: Toll-like receptor 9 is a protein that in humans is encoded by the TLR9 gene. The protein encoded by this gene is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. Studies in mice and human indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response.
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分子量
- 116 kDa
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基因ID
- 54106
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途径
- TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
抗原
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