MGEA5 抗体 (C-Term)
Quick Overview for MGEA5 抗体 (C-Term) (ABIN7602902)
抗原
See all MGEA5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- Anti-MGEA5/OGA Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-MGEA5/OGA Antibody Picoband® (ABIN7602902). Tested in Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at C-terminus of human OGA, identical to the related mouse and rat sequences.
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亚型
- IgG
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anti-Meningioma Expressed Antigen 5 (Hyaluronidase) (MGEA5) (AA 6-240) antibody
MGEA5 适用: 人 WB, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Meningioma Expressed Antigen 5 (Hyaluronidase) (MGEA5) (AA 319-450) antibodyMGEA5 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Meningioma Expressed Antigen 5 (Hyaluronidase) (MGEA5) (AA 83-222) antibodyMGEA5 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Meningioma Expressed Antigen 5 (Hyaluronidase) (MGEA5) (AA 236-269) antibodyMGEA5 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB57955 unconjugated
anti-Meningioma Expressed Antigen 5 (Hyaluronidase) (MGEA5) (AA 823-916) antibodyMGEA5 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1C7 unconjugated
anti-Meningioma Expressed Antigen 5 (Hyaluronidase) (MGEA5) (N-Term) antibodyMGEA5 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Meningioma Expressed Antigen 5 (Hyaluronidase) (MGEA5) antibodyMGEA5 适用: 人 WB, ELISA 宿主: 兔 Monoclonal 8D12 unconjugated Recombinant Antibody
anti-Meningioma Expressed Antigen 5 (Hyaluronidase) (MGEA5) (AA 823-916) antibodyMGEA5 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Meningioma Expressed Antigen 5 (Hyaluronidase) (MGEA5) (AA 1-916) antibodyMGEA5 适用: 人 IP 宿主: 兔 Polyclonal unconjugated
anti-Meningioma Expressed Antigen 5 (Hyaluronidase) (MGEA5) (AA 1-916) antibodyMGEA5 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
1. Comtesse, N., Maldener, E., Meese, E. Identification of a nuclear variant of MGEA5, a cytoplasmic hyaluronidase and a beta-N-acetylglucosaminidase. Biochem. Biophys. Res. Commun. 283: 634-640, 2001. 2. Forsythe, M. E., Love, D. C., Lazarus, B. D., Kim, E. J., Prinz, W. A., Ashwell, G., Krause, M. W., Hanover, J. A. Caenorhabditis elegans ortholog of a diabetes susceptibility locus: oga-1 (O-GlcNAcase) knockout impacts O-GlcNAc cycling, metabolism, and dauer. Proc. Nat. Acad. Sci. 103: 11952-11957, 2006. 3. Gao, Y., Wells, L., Comer, F. I., Parker, G. J., Hart, G. W. Dynamic O-glycosylation of nuclear and cytosolic proteins: cloning and characterization of a neutral, cytosolic, beta-N-acetylglucosaminidase from human brain. J. Biol. Chem. 276: 9838-9845, 2001. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- MGEA5 (Meningioma Expressed Antigen 5 (Hyaluronidase) (MGEA5))
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别名
- OGA
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背景
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Synonyms: Protein Bop, BH3-only protein, Retrotransposon Gag-like protein 10, RTL10, BOP, C22orf29
Tissue Specificity: Ubiquitously expressed.
Background: Protein O-GlcNAcase (EC 3.2.1.169, OGA, glycoside hydrolase O-GlcNAcase, O-GlcNAcase, BtGH84, O-GlcNAc hydrolase) is an enzyme with systematic name (protein)-3-O- (N-acetyl-D-glucosaminyl)-L-serine/threonine N-acetylglucosaminyl hydrolase. The dynamic modification of cytoplasmic and nuclear proteins by O-linked N-acetylglucosamine (O-GlcNAc) addition and removal on serine and threonine residues is catalyzed by OGT (MIM 300255), which adds O-GlcNAc, and MGEA5, a glycosidase that removes O-GlcNAc modifications.
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分子量
- 130 kDa
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基因ID
- 10724
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UniProt
- O60502
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途径
- Positive Regulation of Peptide Hormone Secretion, Regulation of Carbohydrate Metabolic Process
抗原
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