HSPA6 抗体 (C-Term)
Quick Overview for HSPA6 抗体 (C-Term) (ABIN7602897)
抗原
See all HSPA6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- Anti-HSPA6 Antibody Picoband®
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产品特性
- Anti-HSPA6 Antibody Picoband® (ABIN7602897). Tested in WB, Flow Cytometry applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human HSPA6, which shares 81.2% amino acid (aa) sequence identity with mouse and rat HSPA6.
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anti-Heat Shock 70kDa Protein 6 (HSP70B') (HSPA6) antibody
HSPA6 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Heat Shock 70kDa Protein 6 (HSP70B') (HSPA6) antibodyHSPA6 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Heat Shock 70kDa Protein 6 (HSP70B') (HSPA6) (AA 474-643) antibodyHSPA6 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Heat Shock 70kDa Protein 6 (HSP70B') (HSPA6) (Center) antibodyHSPA6 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Heat Shock 70kDa Protein 6 (HSP70B') (HSPA6) (AA 544-571), (C-Term) antibodyHSPA6 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB22779 unconjugated
anti-Heat Shock 70kDa Protein 6 (HSP70B') (HSPA6) (AA 1-387) antibodyHSPA6 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Heat Shock 70kDa Protein 6 (HSP70B') (HSPA6) antibodyHSPA6 适用: 人 WB, FACS, IF 宿主: 小鼠 Monoclonal 1H3 unconjugated
anti-Heat Shock 70kDa Protein 6 (HSP70B') (HSPA6) antibodyHSPA6 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Heat Shock 70kDa Protein 6 (HSP70B') (HSPA6) (AA 1-637) antibodyHSPA6 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Heat Shock 70kDa Protein 6 (HSP70B') (HSPA6) (AA 544-643) antibodyHSPA6 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 6H7 unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
1. Brzustowicz, L. M., Hayter, J. E., Hodgkinson, K. A., Chow, E. W. C., Bassett, A. S. Fine mapping of the schizophrenia susceptibility locus on chromosome 1q22. Hum. Hered. 54: 199-209, 2002. 2. Grosz, M. D., Womack, J. E., Skow, L. C. Syntenic conservation of HSP70 genes in cattle and humans. Genomics 14: 863-868, 1992. 3. Leung, T. K. C., Hall, C., Rajendran, M., Spurr, N. K., Lim, L. The human heat-shock genes HSPA6 and HSPA7 are both expressed and localize to chromosome 1. Genomics 12: 74-79, 1992. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- HSPA6 (Heat Shock 70kDa Protein 6 (HSP70B') (HSPA6))
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别名
- HSPA6
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背景
- Heat shock 70 kDa protein 6 is a protein that in humans is encoded by the HSPA6 gene. The HSPA6 gene, also known as heat shock 70 kDa protein 6, encodes a member of the heat shock protein 70 (HSP70) family, which functions as molecular chaperones involved in protein folding, unfolding, and transport under stress conditions. HSPA6 is induced in response to cellular stressors such as heat shock, oxidative stress, and exposure to toxic agents, where it assists in protein refolding and prevents protein aggregation, thus promoting cell survival. While HSPA6 shares significant sequence homology with other HSP70 family members, it exhibits distinct expression patterns and functional properties in different tissues and cellular contexts. Its role in various physiological processes and diseases, including neurodegenerative disorders, cancer, and cardiovascular diseases, is under investigation. Understanding the molecular mechanisms underlying HSPA6 function is crucial for elucidating its role in cellular stress responses and its potential as a therapeutic target for stress-related diseases.
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分子量
- 71 kDa
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基因ID
- 3310
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UniProt
- P17066
抗原
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