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HSPA6 抗体 (AA 474-643)

HSPA6 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6142046
发货至: 中国
  • 抗原 See all HSPA6 抗体
    HSPA6 (Heat Shock 70kDa Protein 6 (HSP70B') (HSPA6))
    抗原表位
    • 15
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 474-643
    适用
    • 39
    • 5
    • 4
    • 1
    宿主
    • 34
    • 5
    克隆类型
    • 34
    • 5
    多克隆
    标记
    • 21
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This HSPA6 antibody is un-conjugated
    应用范围
    • 35
    • 13
    • 13
    • 10
    • 8
    • 6
    • 5
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    PQIEVTFDID ANGILSVTAT DRSTGKANKI TITNDKGRLS KEEVERMVHE AEQYKAEDEA QRDRVAAKNS LEAHVFHVKG SLQEESLRDK IPEEDRRKMQ DKCREVLAWL EHNQLAEKEE YEHQKRELEQ ICRPIFSRLY GGPGVPGGSS CGTQARQGDP STGPIIEEVD
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 474-643 of human HSPA6 (NP_002146.2).
    亚型
    IgG
    Top Product
    Discover our top product HSPA6 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000,IHC,1:50 - 1:200
    说明

    HIGH QUALITY

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    HSPA6 (Heat Shock 70kDa Protein 6 (HSP70B') (HSPA6))
    别名
    HSPA6 (HSPA6 产品)
    别名
    HSPA6 antibody, HSP70B' antibody, heat shock protein family A (Hsp70) member 6 antibody, HSPA6 antibody
    背景
    Molecular chaperone implicated in a wide variety of cellular processes, including protection of the proteome from stress, folding and transport of newly synthesized polypeptides, activation of proteolysis of misfolded proteins and the formation and dissociation of protein complexes. Plays a pivotal role in the protein quality control system, ensuring the correct folding of proteins, the re-folding of misfolded proteins and controlling the targeting of proteins for subsequent degradation. This is achieved through cycles of ATP binding, ATP hydrolysis and ADP release, mediated by co-chaperones. The affinity for polypeptides is regulated by its nucleotide bound state. In the ATP-bound form, it has a low affinity for substrate proteins. However, upon hydrolysis of the ATP to ADP, it undergoes a conformational change that increases its affinity for substrate proteins. It goes through repeated cycles of ATP hydrolysis and nucleotide exchange, which permits cycles of substrate binding and release.,HSPA6,HSP70B,Cancer,Tumor biomarkers,Signal Transduction,Cell Biology & Developmental Biology,Endocrine & Metabolism,Mitochondrial metabolism,HSPA6
    分子量
    71 kDa
    基因ID
    3310
    UniProt
    P17066
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