电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

HSF1 抗体 (C-Term)

This anti-HSF1 antibody is a 兔 多克隆 antibody detecting HSF1 in WB, IHC 和 FACS. Suitable for 人.
产品编号 ABIN7602894
发货至: 中国

Quick Overview for HSF1 抗体 (C-Term) (ABIN7602894)

抗原

See all HSF1 抗体
HSF1 (Heat Shock Factor Protein 1 (HSF1))

适用

  • 145
  • 90
  • 40
  • 14
  • 8
  • 7
  • 7
  • 6
  • 6
  • 4
  • 4
  • 1
  • 1
  • 1

宿主

  • 134
  • 38
  • 8
  • 1

克隆类型

  • 120
  • 60
多克隆

标记

  • 107
  • 10
  • 10
  • 8
  • 7
  • 5
  • 5
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This HSF1 antibody is un-conjugated

应用范围

  • 145
  • 98
  • 84
  • 55
  • 53
  • 40
  • 34
  • 19
  • 15
  • 15
  • 9
  • 5
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
  • 抗原表位

    • 16
    • 16
    • 15
    • 14
    • 11
    • 9
    • 9
    • 7
    • 7
    • 7
    • 6
    • 6
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    原理

    Anti-HSF1 Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-HSF1 Antibody Picoband® (ABIN7602894). Tested in Flow Cytometry, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human HSF1, identical to the related mouse and rat sequences.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.25 μg/mL/mL, Human
    Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/mL/1x10^6 cells, Human
    1. Christians, E., Davis, A. A., Thomas, S. D., Benjamin, I. J. Maternal effect of Hsf1 on reproductive success. Nature 407: 693-694, 2000. 2. Schuetz, T. J. Personal Communication. Boston, Mass. 10/3/1991.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    HSF1 (Heat Shock Factor Protein 1 (HSF1))

    别名

    HSF1

    背景

    Synonyms: C-reactive protein, C-reactive protein (1-205), CRP, PTX1

    Tissue Specificity: Found in plasma.

    Background: HSF1(HEAT-SHOCK TRANSCRIPTION FACTOR 1), also called HEAT-SHOCK FACTOR 1, is a protein that in humans is encoded by the HSF1 gene. The product of HSF1 gene is a heat-shock transcription factor. The International Radiation Hybrid Mapping Consortium maps the HSF1 gene to chromosome 8. HSF1 exists as an inactive monomer in a complex with Hsp40/Hsp70 and Hsp90. Upon stress, such as elevated temperature, HSF1 is released from the chaperone complex and trimerizes. HSF1 is then transported into the nucleus where it is hyperphosphorylated and binds to DNA containing heat shock elements. HSF1's target genes include major inducible heat shock proteins such as Hsp72, and interestingly, noncoding RNA within Satellite III repeat regions. In a novel in vitro system human HSF1 can be activated by nonnative protein, heat, and geldanamycin. HSR1 is constitutively expressed in human and rodent cells and its homologs are functionally interchangeable. Furthermore, Hsf1-deficient mice had a longer free-running period than wildtype littermates.

    分子量

    80 kDa

    基因ID

    3297

    UniProt

    Q00613
You are here:
Chat with us!