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NOD1 抗体 (C-Term)

This 兔 多克隆 antibody specifically detects NOD1 in WB. It exhibits reactivity toward 猴.
产品编号 ABIN7602813
发货至: 中国
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Quick Overview for NOD1 抗体 (C-Term) (ABIN7602813)

抗原

See all NOD1 抗体
NOD1 (Nucleotide-Binding Oligomerization Domain Containing 1 (NOD1))

适用

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宿主

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克隆类型

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多克隆

标记

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This NOD1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    C-Term

    原理

    Anti-CARD4/NOD1 Antibody

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-CARD4/NOD1 Antibody (ABIN7602813). Tested in WB applications. This antibody reacts with Monkey. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human CARD4/NOD1, which shares 88.2% and 93.8% amino acid (aa) sequence identity with mouse and rat CARD4/NOD1, respectively.

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Monkey

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    NOD1 (Nucleotide-Binding Oligomerization Domain Containing 1 (NOD1))

    别名

    NOD1

    背景

    Synonyms: Tyrosine-protein kinase SYK, Spleen tyrosine kinase, p72-Syk, SYK

    Tissue Specificity: Widely expressed in hematopoietic cells. Expressed in neutrophils. Within the B-cell compartment, expressed from pro- and pre-B cells to plasma cells.

    Background: Nucleotide-binding oligomerization domain-containing protein 1, also known as CARD4, is a protein receptor that in humans is encoded by the NOD1 gene. NOD1 is a member of NOD-like receptor protein family and is a close relative of NOD2. NOD1 is mapped to 7p14.3. It recognizes bacterial molecules and stimulates an immune reaction. NOD1 protein contains a caspase recruitment domain (CARD). This gene is an intracellular pattern recognition receptor, which is similar in structure to resistant proteins of plants, and mediates innate and acquired immunity by recognizing bacterial molecules containing D-glutamyl-meso-diaminopimelic acid (iE-DAP) moiety. What wore, it has been shown that NOD1 can sense cytosolic microbial products by monitoring the activation state of small Rho GTPases.

    分子量

    108 kDa

    基因ID

    10392

    UniProt

    Q9Y239

    途径

    Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades, Inflammasome
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