ALDH6A1 抗体 (C-Term)
Quick Overview for ALDH6A1 抗体 (C-Term) (ABIN7602810)
抗原
See all ALDH6A1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- C-Term
-
原理
- Anti-ALDH6A1 Antibody Picoband®
-
交叉反应 （详细）
- No cross-reactivity with other proteins.
-
产品特性
- Anti-ALDH6A1 Antibody Picoband® (ABIN7602810). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human ALDH6A1, identical to the related mouse and rat sequences.
-
亚型
- IgG
-
-
anti-Aldehyde Dehydrogenase 6 Family, Member A1 (ALDH6A1) (AA 1-195) antibody
ALDH6A1 适用: 人 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 6H9B8 unconjugated
anti-Aldehyde Dehydrogenase 6 Family, Member A1 (ALDH6A1) antibodyALDH6A1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Aldehyde Dehydrogenase 6 Family, Member A1 (ALDH6A1) antibodyALDH6A1 适用: 人 WB, IHC (p), IF 宿主: 小鼠 Monoclonal 7C4 unconjugated
anti-Aldehyde Dehydrogenase 6 Family, Member A1 (ALDH6A1) antibodyALDH6A1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Aldehyde Dehydrogenase 6 Family, Member A1 (ALDH6A1) (AA 1-535) antibodyALDH6A1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Aldehyde Dehydrogenase 6 Family, Member A1 (ALDH6A1) (AA 326-535) antibodyALDH6A1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Aldehyde Dehydrogenase 6 Family, Member A1 (ALDH6A1) antibodyALDH6A1 适用: 人 WB, IHC (p), IF 宿主: 小鼠 Monoclonal 147CT8-3-4 unconjugated
anti-Aldehyde Dehydrogenase 6 Family, Member A1 (ALDH6A1) (AA 274-399) antibodyALDH6A1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Aldehyde Dehydrogenase 6 Family, Member A1 (ALDH6A1) (AA 487-496) antibodyVerified ALDH6A1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Aldehyde Dehydrogenase 6 Family, Member A1 (ALDH6A1) (AA 262-272) antibodyVerified ALDH6A1 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
-
-
应用备注
-
Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human
1. Chambliss, K. L., Gray, R. G. F., Rylance, G., Pollitt, R. J., Gibson, K. M. Molecular characterization of methylmalonate semialdehyde dehydrogenase deficiency. J. Inherit. Metab. Dis. 23: 497-504, 2000. 2. Dobrowolski, S. F., Alodaib, A., Karunanidhi, A., Basu, S., Holecko, M., Lichter-Konecki, U., Pappan, K. L., Vockley, J. Clinical, biochemical, mitochondrial, and metabolomic aspects of methylmalonate semialdehyde dehydrogenase deficiency: report of a fifth case. Molec. Genet. Metab. 129: 272-277, 2020. 3. Gray, R. G. F., Pollitt, R. J., Webley, J. Methylmalonic semialdehyde dehydrogenase deficiency: demonstration of defective valine and beta-alanine metabolism and reduced malonic semialdehyde dehydrogenase activity in cultured fibroblasts. Biochem. Med. Metab. Biol. 38: 121-124, 1987. -
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
-
-
- ALDH6A1 (Aldehyde Dehydrogenase 6 Family, Member A1 (ALDH6A1))
-
别名
- ALDH6A1
-
背景
-
Synonyms: Pannexin-2, PANX2
Tissue Specificity: Expressed in fetal and adult brain. Also detected in fetal liver and skeletal muscle, but not in their adult counterparts.
Background: Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial (MMSDH) is an enzyme that in humans is encoded by the ALDH6A1 gene. This gene encodes a member of the aldehyde dehydrogenase protein family. The encoded protein is a mitochondrial methylmalonate semialdehyde dehydrogenase that plays a role in the valine and pyrimidine catabolic pathways. This protein catalyzes the irreversible oxidative decarboxylation of malonate and methylmalonate semialdehydes to acetyl- and propionyl-CoA. Methylmalonate semialdehyde dehydrogenase deficiency is characterized by elevated beta-alanine, 3-hydroxypropionic acid, and both isomers of 3-amino and 3-hydroxyisobutyric acids in urine organic acids. Alternate splicing results in multiple transcript variants.
-
分子量
- 58 kDa
-
基因ID
- 4329
-
UniProt
- Q02252
-
途径
- Brown Fat Cell Differentiation
抗原
-
