UCHL1 抗体 (C-Term)
Quick Overview for UCHL1 抗体 (C-Term) (ABIN7602794)
抗原
See all UCHL1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- C-Term
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原理
- Anti-PGP9.5 Antibody Picoband® (monoclonal, 3E4)
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-PGP9.5 Antibody Picoband® (monoclonal, 3E4) (ABIN7602794). Tested in Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human PGP9.5, different from the related mouse and rat sequences by two amino acids.
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亚型
- IgG1
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anti-Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1) (AA 2-223) antibody
UCHL1 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1) (AA 2-223) antibodyUCHL1 适用: 小鼠 WB, IHC, FACS, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1) (AA 2-223) antibodyUCHL1 适用: 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1) antibodyUCHL1 适用: 人, 大鼠 WB, IHC, IF, FACS, StM 宿主: 小鼠 Monoclonal rUCHL1-775 unconjugated Recombinant Antibody
anti-Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1) (AA 59-223) antibodyUCHL1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1) (AA 187-216), (C-Term) antibodyUCHL1 适用: 人, 大鼠, 小鼠 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB7379 unconjugated
anti-Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1) antibodyMicroarray verified UCHL1 适用: 人, 小鼠 IHC 宿主: 小鼠 Monoclonal MAB215939 unconjugated
anti-Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1) (AA 1-223) antibodyUCHL1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1B8-4D2 unconjugated
anti-Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1) antibodyUCHL1 适用: 人, 大鼠, 小鼠, Cow, Pig WB, IHC, IF, FACS, StM 宿主: 小鼠 Monoclonal 31A3 unconjugated
anti-Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1) (AA 16-46), (N-Term) antibodyUCHL1 适用: 人, 小鼠 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB04183 unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
1. "Entrez Gene: UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)". 2. Das C, Hoang QQ, Kreinbring CA, Luchansky SJ, Meray RK, Ray SS, Lansbury PT, Ringe D, Petsko GA (Mar 2006). "Structural basis for conformational plasticity of the Parkinson's disease-associated ubiquitin hydrolase UCH-L1". Proceedings of the National Academy of Sciences of the United States of America 103 (12): 4675-80. 3. Doran JF, Jackson P, Kynoch PA, Thompson RJ (Jun 1983). "Isolation of PGP 9.5, a new human neurone-specific protein detected by high-resolution two-dimensional electrophoresis". Journal of Neurochemistry 40 (6): 1542-7. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- UCHL1 (Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1))
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别名
- UCHL1
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背景
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Synonyms: ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial, CLPX
Tissue Specificity: Higher expression in skeletal muscle and heart and to a lesser extent in liver, brain, placenta, lung, kidney and pancreas.
Background: UCH-L1, also known as PGP9.5, is a member of a gene family whose products hydrolyze small C-terminal adducts of ubiquitin to generate the ubiquitin monomer. Expression of UCH-L1 is highly specific to neurons and to cells of the diffuse neuroendocrine system and their tumors. It is abundantly present in all neurons (accounts for 1-2 % of total brain protein), expressed specifically in neurons and testis/ovary. The catalytic triad of UCH-L1 contains a cysteine at position 90, an aspartate at position 176, and a histidine at position 161 that are responsible for its hydrolase activity.
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分子量
- 27 kDa
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基因ID
- 7345
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UniProt
- P09936
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途径
- Feeding Behaviour
抗原
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