UCHL1 抗体 (C-Term)
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- 抗原 See all UCHL1 抗体
- UCHL1 (Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1))
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抗原表位
- AA 120-153, C-Term
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适用
- 人, 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This UCHL1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- Rabbit IgG polyclonal antibody for Ubiquitin carboxyl-terminal hydrolase isozyme L1(UCHL1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
- 序列
- ETEKMSPEDR AKCFEKNEAI QAAHDAVAQE GQCR
- 交叉反应 (详细)
- No cross reactivity with other proteins.
- 产品特性
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Rabbit IgG polyclonal antibody for Ubiquitin carboxyl-terminal hydrolase isozyme L1(UCHL1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: ubiquitin C-terminal hydrolase L1
Protein Name: Ubiquitin carboxyl-terminal hydrolase isozyme L1 - 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human PGP9.5 (120-153aa ETEKMSPEDRAKCFEKNEAIQAAHDAVAQEGQCR), different from the related mouse and rat sequences by two amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product UCHL1 Primary Antibody
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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Nude mice multi-drug resistance model of orthotopic transplantation of liver neoplasm and Tc-99m MIBI SPECT on p-glycoprotein." in: World journal of gastroenterology, Vol. 11, Issue 22, pp. 3335-8, (2005) (PubMed).
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Nude mice multi-drug resistance model of orthotopic transplantation of liver neoplasm and Tc-99m MIBI SPECT on p-glycoprotein." in: World journal of gastroenterology, Vol. 11, Issue 22, pp. 3335-8, (2005) (PubMed).
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- 抗原
- UCHL1 (Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1))
- 别名
- UCHL1 (UCHL1 产品)
- 别名
- PARK5 antibody, PGP 9.5 antibody, PGP9.5 antibody, PGP95 antibody, Uch-L1 antibody, UCH-L1 antibody, UCHL1 antibody, cb358 antibody, wu:fc55h08 antibody, park5 antibody, pgp9.5 antibody, uch-l1 antibody, MGC132191 antibody, uchl1 antibody, AW822034 antibody, C88048 antibody, R75593 antibody, UCHL-1 antibody, gad antibody, ubiquitin C-terminal hydrolase L1 antibody, ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) antibody, ubiquitin C-terminal hydrolase L1 L homeolog antibody, ubiquitin carboxyl-terminal esterase L1 antibody, ubiquitin carboxy-terminal hydrolase L1 antibody, UCHL1 antibody, uchl1 antibody, uchl1.L antibody, LOC100304750 antibody, Uchl1 antibody
- 背景
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UCH-L1, also known as PGP9.5, is a member of a gene family whose products hydrolyze small C-terminal adducts of ubiquitin to generate the ubiquitin monomer. Expression of UCH-L1 is highly specific to neurons and to cells of the diffuse neuroendocrine system and their tumors. It is abundantly present in all neurons (accounts for 1-2 % of total brain protein), expressed specifically in neurons and testis/ovary. The catalytic triad of UCH-L1 contains a cysteine at position 90, an aspartate at position 176, and a histidine at position 161 that are responsible for its hydrolase activity.
Synonyms: Neuron cytoplasmic protein 9.5 antibody|OTTHUMP00000218137 antibody|OTTHUMP00000218139 antibody|OTTHUMP00000218140 antibody| OTTHUMP00000218141 antibody|Park 5 antibody|PARK5 antibody|PGP 9.5 antibody|PGP9.5 antibody|PGP95 antibody|Protein gene product 9.5 antibody|Ubiquitin C terminal esterase L1 antibody|Ubiquitin C terminal hydrolase antibody|Ubiquitin carboxyl terminal esterase L1 antibody|Ubiquitin carboxyl terminal hydrolase isozyme L1 antibody|Ubiquitin carboxyl-terminal hydrolase isozyme L1 antibody|Ubiquitin thioesterase L1 antibody|Ubiquitin thiolesterase antibody|Ubiquitin thiolesterase L1 antibody|UCH-L1 antibody|UCHL1 antibody| UCHL1_HUMAN antibody - 基因ID
- 7345
- UniProt
- P09936
- 途径
- Feeding Behaviour
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