SDHA 抗体 (C-Term)
Quick Overview for SDHA 抗体 (C-Term) (ABIN7602753)
抗原
See all SDHA 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- Anti-SDHA Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-SDHA Antibody Picoband® (ABIN7602753). Tested in Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human SDHA, identical to the related mouse and rat sequences.
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亚型
- IgG
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anti-Succinate Dehydrogenase Complex, Subunit A, Flavoprotein (Fp) (SDHA) (AA 385-664) antibody
SDHA 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Succinate Dehydrogenase Complex, Subunit A, Flavoprotein (Fp) (SDHA) (AA 4-300) antibodySDHA 适用: 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Succinate Dehydrogenase Complex, Subunit A, Flavoprotein (Fp) (SDHA) (N-Term) antibodySDHA 适用: 人, 小鼠 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Succinate Dehydrogenase Complex, Subunit A, Flavoprotein (Fp) (SDHA) (AA 44-293) antibodySDHA 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Succinate Dehydrogenase Complex, Subunit A, Flavoprotein (Fp) (SDHA) antibodySDHA 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Succinate Dehydrogenase Complex, Subunit A, Flavoprotein (Fp) (SDHA) (C-Term) antibodySDHA 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Succinate Dehydrogenase Complex, Subunit A, Flavoprotein (Fp) (SDHA) (AA 44-664) antibodySDHA 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Succinate Dehydrogenase Complex, Subunit A, Flavoprotein (Fp) (SDHA) antibodySDHA 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Succinate Dehydrogenase Complex, Subunit A, Flavoprotein (Fp) (SDHA) (C-Term) antibodySDHA 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Succinate Dehydrogenase Complex, Subunit A, Flavoprotein (Fp) (SDHA) (Internal Region) antibodySDHA 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human, Mouse, Rat
1. Alston, C. L., Davison, J. E., Meloni, F., van der Westhuizen, F. H., He, L., Hornig-Do, H.-T., Peet, A. C., Gissen, P., Goffrini, P., Ferrero, I., Wassmer, E., McFarland, R., Taylor, R. W. Recessive germline SDHA and SDHB mutations causing leukodystrophy and isolated mitochondrial complex II deficiency. J. Med. Genet. 49: 569-577, 2012. 2. Bourgeron, T., Rustin, P., Chretien, D., Birch-Machin, M., Bourgeois, M., Viegas-Pequignot, E., Munnich, A., Rotig, A. Mutation of a nuclear succinate dehydrogenase gene results in mitochondrial respiratory chain deficiency. Nature Genet. 11: 144-149, 1995. 3. Burnichon, N, Briere, J.-J., Libe, R., Vescovo, L., Riviere, J., Tissier, F., Jouanno, E., Jeunemaitre, X., Benit, P., Tzagoloff, A., Rustin, P., Bertherat, J., Favier, J., Gimenez-Roqueplo, A.-P. SDHA is a tumor suppressor gene causing paraganglioma. Hum. Molec. Genet. 19: 3011-3020, 2010. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- SDHA (Succinate Dehydrogenase Complex, Subunit A, Flavoprotein (Fp) (SDHA))
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别名
- SDHA
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背景
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Synonyms: Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial, Flavoprotein subunit of complex II, Fp, SDHA, SDH2, SDHF
Tissue Specificity: Expressed in adipose tissue, heart, brain, skeletal muscle, pancreas, thymus, prostate, testis, ovary, small intestine and colon. Highest levels in adipose tissue, small intestine and colon.
Background: Succinate dehydrogenase complex, subunit A, flavoprotein variant is a protein that in humans is encoded by the SDHA gene. It is mapped to 5p15.33. This gene encodes a major catalytic subunit of succinate-ubiquinone oxidoreductase, a complex of the mitochondrial respiratory chain. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. Mutations in this gene have been associated with a form of mitochondrial respiratory chain deficiency known as Leigh Syndrome. A pseudogene has been identified on chromosome 3q29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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分子量
- 73 kDa
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基因ID
- 6389
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UniProt
- P31040
抗原
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