Nerve Growth Factor 抗体 (C-Term)
Quick Overview for Nerve Growth Factor 抗体 (C-Term) (ABIN7602750)
抗原
See all Nerve Growth Factor (NGF) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- Anti-NGF Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-NGF Antibody Picoband® (ABIN7602750). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human NGF, which shares 91.3% amino acid (aa) sequence identity with both mouse and rat NGF.
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亚型
- IgG
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anti-Nerve Growth Factor (NGF) antibody
NGF 适用: 人 WB, ELISA, Neut 宿主: 兔 Polyclonal unconjugated
anti-Nerve Growth Factor (NGF) (AA 19-241) antibodyNGF 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nerve Growth Factor (NGF) (AA 162-173), (N-Term) antibodyNGF 适用: 人, 大鼠, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Nerve Growth Factor (NGF) antibodyNGF 适用: 人, 大鼠, 小鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Nerve Growth Factor (NGF) (AA 19-239) antibodyNGF 适用: 人 WB, ICC, IF 宿主: 小鼠 Monoclonal C1 unconjugated
anti-Nerve Growth Factor (NGF) (AA 122-218) antibodyNGF 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Nerve Growth Factor (NGF) (AA 122-241) antibodyNGF 适用: Cow WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nerve Growth Factor (NGF) antibodyNGF 适用: 人 WB, IHC, ELISA 宿主: 兔 Monoclonal 5F10 unconjugated Recombinant Antibody
anti-Nerve Growth Factor (NGF) (N-Term) antibodyNGF 适用: 人, 大鼠, 小鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Nerve Growth Factor (NGF) antibody (Biotin)NGF 适用: 人 WB, ELISA, Neut 宿主: 兔 Polyclonal Biotin
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
1. Breakefield, X. O., Orloff, G., Castiglione, C., Coussens, L., Axelrod, F. B., Ullrich, A. Structural gene for beta-nerve growth factor not defective in familial dysautonomia. Proc. Nat. Acad. Sci. 81: 4213-4216, 1984. 2. Carrier, A., Rosier, M.-F., Guillemot, F., Goguel, A.-F., Pulcini, F., Bernheim, A., Auffray, C., Devignes, M.-D. Integrated physical, genetic, and genic map covering 3 Mb around the human NGF gene (NGFB) at 1p13. Genomics 31: 80-89, 1996. 3. Carvalho, O. P., Thornton, G. K., Hertecant, J., Houlden, H., Nicholas, A. K., Cox, J. J., Rielly, M., Al-Gazali, L., Woods, C. G. A novel NGF mutation clarifies the molecular mechanism and extends the phenotypic spectrum of the HSAN5 neuropathy. J. Med. Genet. 48: 131-135, 2011. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- Nerve Growth Factor (NGF)
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别名
- NGF
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背景
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Synonyms: Beta-nerve growth factor, Beta-NGF, NGF, NGFB
Tissue Specificity: Expressed in thymus, peripheral leukocytes as T-cells and spleen. Isoforms A are preferentially expressed in effector T-cells (thymus and peripheral leukocytes) whereas isoforms B and isoforms C are preferentially expressed in naive T-cells (spleen). Isoforms B are expressed in naive T-cells after first antigen exposure and isoforms A are expressed in effector T-cells after second antigen exposure. Isoforms IA are widely expressed but not detected in liver nor pancreas, neural expression is strongest in corpus callosum. Isoforms IB are expressed mostly in muscle, cerebellum, placenta and thymus, neural expression in fetal and adult brain, strongest in corpus callosum.
Background: Nerve growth factor (NGF) is a neurotrophic factor and neuropeptide primarily involved in the regulation of growth, maintenance, proliferation, and survival of certain target neurons. It is mapped to 1p13.2. This gene is a member of the NGF-beta family and encodes a secreted protein which homodimerizes and is incorporated into a larger complex. This protein has nerve growth stimulating activity and the complex is involved in the regulation of growth and the differentiation of sympathetic and certain sensory neurons. Mutations in this gene have been associated with hereditary sensory and autonomic neuropathy, type 5 (HSAN5), and dysregulation of this gene's expression is associated with allergic rhinitis.
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分子量
- 27 kDa
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基因ID
- 4803
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UniProt
- P01138
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途径
- Regulation of Cell Size
抗原
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