ALKBH1 抗体 (C-Term)
Quick Overview for ALKBH1 抗体 (C-Term) (ABIN7602742)
抗原
See all ALKBH1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- Anti-ALKBH1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-ALKBH1 Antibody (ABIN7602742). Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human ALKBH1, which shares 81.3% and 84.4% amino acid (aa) sequence identity with mouse and rat ALKBH1, respectively.
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亚型
- IgG
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anti-AlkB, Alkylation Repair Homolog 1 (ALKBH1) antibody
ALKBH1 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-AlkB, Alkylation Repair Homolog 1 (ALKBH1) (AA 1-389) antibodyALKBH1 适用: 人 WB, IF, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-AlkB, Alkylation Repair Homolog 1 (ALKBH1) (AA 110-389) antibodyALKBH1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-AlkB, Alkylation Repair Homolog 1 (ALKBH1) (AA 1-389) antibodyALKBH1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-AlkB, Alkylation Repair Homolog 1 (ALKBH1) (AA 110-389) antibodyALKBH1 适用: 人 WB, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-AlkB, Alkylation Repair Homolog 1 (ALKBH1) (AA 110-389) antibodyALKBH1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-AlkB, Alkylation Repair Homolog 1 (ALKBH1) antibodyALKBH1 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-AlkB, Alkylation Repair Homolog 1 (ALKBH1) (AA 97-146) antibodyALKBH1 适用: 人, 小鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-AlkB, Alkylation Repair Homolog 1 (ALKBH1) (Center) antibodyALKBH1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-AlkB, Alkylation Repair Homolog 1 (ALKBH1) (N-Term) antibodyALKBH1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.25 μg/mL, Human
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
1. Haag, S., Sloan, K. E., Ranjan, N., Warda, A. S., Kretschmer, J., Blessing, C., Hubner, B., Seikowski, J., Dennerlein, S., Rehling, P., Rodnina, M., Hobartner, C., Bohnsack, M. T. NSUN3 and ABH1 modify the wobble position of mt-tRNA(Met) to expand codon recognition in mitochondrial translation. EMBO J. 35: 2104-2119, 2016. 2. Tsujikawa, K., Koike, K., Kitae, K., Shinkawa, A., Arima, H., Suzuki, T., Tsuchiya, M., Makino, Y., Furukawa, T., Konishi, N., Yamamoto, H. Expression and sub-cellular localization of human ABH family molecules. J. Cell. Molec. Med. 11: 1105-1116, 2007. 3. Wei, Y. F., Carter, K. C., Wang, R. P., Shell, B. K. Molecular cloning and functional analysis of a human cDNA encoding an Escherichia coli AlkB homolog, a protein involved in DNA alkylation damage repair. Nucleic Acids Res. 24: 931-937, 1996. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- ALKBH1 (AlkB, Alkylation Repair Homolog 1 (ALKBH1))
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别名
- ALKBH1
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背景
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Synonyms: Nucleic acid dioxygenase ALKBH1, Alkylated DNA repair protein alkB homolog 1, Alpha-ketoglutarate-dependent dioxygenase ABH1, DNA 6mA demethylase, DNA N6-methyl adenine demethylase ALKBH1, DNA lyase ABH1, DNA oxidative demethylase ALKBH1, mRNA N (3)-methylcytidine demethylase, ALKBH1, ABH, ABH1, ALKBH
Tissue Specificity: Ubiquitous.
Background: Nucleic acid dioxygenase ALKBH1 is an enzyme that in humans is encoded by the ALKBH1 gene. It is mapped to 14q24.3. This gene encodes a homolog to the E. coli alkB gene product. The E. coli alkB protein is part of the adaptive response mechanism of DNA alkylation damage repair. It is involved in damage reversal by oxidative demethylation of 1-methyladenine and 3-methylcytosine.
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分子量
- 43 kDa
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基因ID
- 8846
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UniProt
- Q13686
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途径
- DNA Damage Repair
抗原
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