OAS3 抗体 (AA 990-1087)
Quick Overview for OAS3 抗体 (AA 990-1087) (ABIN7602725)
抗原
See all OAS3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 990-1087
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原理
- Anti-OAS3 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-OAS3 Antibody Picoband® (ABIN7602725). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human OAS3 recombinant protein (Position: N990-V1087).
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亚型
- IgG
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anti-2'-5' Oligoadenylate Synthetase 3 (OAS3) (AA 424-565) antibody
OAS3 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-2'-5' Oligoadenylate Synthetase 3 (OAS3) antibodyOAS3 适用: 人, 小鼠, 大鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-2'-5' Oligoadenylate Synthetase 3 (OAS3) antibodyOAS3 适用: 人, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-2'-5' Oligoadenylate Synthetase 3 (OAS3) (AA 320-620) antibodyOAS3 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-2'-5' Oligoadenylate Synthetase 3 (OAS3) (AA 1056-1087), (C-Term) antibodyOAS3 适用: 人 WB 宿主: 兔 Polyclonal RB1945 unconjugated
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应用备注
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Western blot, 0.1-0.25 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Hovanessian, A. G., Laurent, A. G., Chebath, J., Galabru, J., Robert, N., Svab, J. Identification of 69-kd and 100-kd forms of 2-5A synthetase in interferon-treated human cells by specific monoclonal antibodies. EMBO J. 6: 1273-1280, 1987. 2. Hovnanian, A., Rebouillat, D., Mattei, M.-G., Levy, E. R., Marie, I., Monaco, A. P., Hovanessian, A. G. The human 2-prime,5-prime-oligoadenylate synthetase locus is composed of three distinct genes clustered on chromosome 12q24.2 encoding the 100-, 69-, and 40- kDa forms. Genomics 52: 267-277, 1998. 3. Lin, R.-J., Yu, H.-P., Chang, W.-C., Liao, C.-L., Lin, Y.-L. Distinct antiviral roles for human 2-prime,5-prime-oligoadenylate synthetase family members against Dengue virus infection. J. Immun. 183: 8035-8043, 2009. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- OAS3 (2'-5' Oligoadenylate Synthetase 3 (OAS3))
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别名
- OAS3
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背景
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Synonyms: 2'-5'-oligoadenylate synthase 3, (2-5')oligo (A) synthase 3, 2-5A synthase 3, p100 OAS, p100OAS, OAS3, P/OKcl.4
Tissue Specificity: Present at high level in placenta trophoblast.
Background: 2'-5'-oligoadenylate synthetase 3 is an enzyme that in humans is encoded by the OAS3 gene. It is mapped to 12q24.13. This gene encodes an enzyme included in the 2', 5' oligoadenylate synthase family. This enzyme is induced by interferons and catalyzes the 2', 5' oligomers of adenosine in order to bind and activate RNase L. This enzyme family plays a significant role in the inhibition of cellular protein synthesis and viral infection resistance.
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分子量
- 123 kDa
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基因ID
- 4940
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UniProt
- Q9Y6K5
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途径
- Hepatitis C
抗原
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