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- 抗原 See all OAS3 抗体
- OAS3 (2'-5' Oligoadenylate Synthetase 3 (OAS3))
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抗原表位
- AA 424-565
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This OAS3 antibody is un-conjugated
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应用范围
- ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human 2\'-5\'-oligoadenylate synthase 3 protein (424-565AA)
- 亚型
- IgG
- Top Product
- Discover our top product OAS3 Primary Antibody
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anti-2'-5' Oligoadenylate Synthetase 3 (OAS3) antibody
OAS3 适用: 人, 大鼠 WB, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-2'-5' Oligoadenylate Synthetase 3 (OAS3) antibodyOAS3 适用: 人, 小鼠, 大鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-2'-5' Oligoadenylate Synthetase 3 (OAS3) (AA 320-620) antibodyOAS3 适用: 人 WB, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-2'-5' Oligoadenylate Synthetase 3 (OAS3) (C-Term) antibodyOAS3 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-2'-5' Oligoadenylate Synthetase 3 (OAS3) (AA 1056-1087), (C-Term) antibodyOAS3 适用: 人 WB 宿主: 兔 Polyclonal RB1945 unconjugated
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- 应用备注
- Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- OAS3 (2'-5' Oligoadenylate Synthetase 3 (OAS3))
- 别名
- OAS3 (OAS3 产品)
- 别名
- p100 antibody, Oasl10 antibody, 2'-5'-oligoadenylate synthetase 3 antibody, 2'-5' oligoadenylate synthetase 3 antibody, OAS3 antibody, Oas3 antibody
- 背景
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Background: Interferon-induced, dsRNA-activated antiviral enzyme which plays a critical role in cellular innate antiviral response. In addition, it may also play a role in other cellular processes such as apoptosis, cell growth, differentiation and gene regulation. Synthesizes preferentially dimers of 2\'-5\'-oligoadenylates (2-5A) from ATP which then bind to the inactive monomeric form of ribonuclease L (RNase L) leading to its dimerization and subsequent activation. Activation of RNase L leads to degradation of cellular as well as viral RNA, resulting in the inhibition of protein synthesis, thus terminating viral replication. Can mediate the antiviral effect via the classical RNase L-dependent pathway or an alternative antiviral pathway independent of RNase L. Displays antiviral activity against Chikungunya virus (CHIKV), Dengue virus, Sindbis virus (SINV) and Semliki forest virus (SFV).
Aliases: (2-5'')oligo(A) synthase 3 antibody, 2 5' oligo(A) synthetase 3 antibody, 2 5'LIGO antibody, 2 5A synthetase 3 antibody, 2''-5''-oligoadenylate synthase 3 antibody, 2-5A synthase 3 antibody, MGC133260 antibody, OAS3 2' 5' oligoadenylate synthetase 3, 100 kDa antibody, OAS3 antibody, OAS3_HUMAN antibody, p100 antibody, p100 OAS antibody, p100OAS antibody
- UniProt
- Q9Y6K5
- 途径
- Hepatitis C
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