NECAB3 抗体 (AA 97-339)
Quick Overview for NECAB3 抗体 (AA 97-339) (ABIN7602707)
抗原
See all NECAB3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 97-339
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原理
- Anti-NECAB3 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-NECAB3 Antibody Picoband® (ABIN7602707). Tested in ELISA, WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human NECAB3 recombinant protein (Position: D97-D339).
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亚型
- IgG
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anti-N-Terminal EF-Hand Calcium Binding Protein 3 (NECAB3) (Internal Region) antibody
NECAB3 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-N-Terminal EF-Hand Calcium Binding Protein 3 (NECAB3) (C-Term) antibodyNECAB3 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-N-Terminal EF-Hand Calcium Binding Protein 3 (NECAB3) (C-Term) antibodyNECAB3 适用: 人, 小鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-N-Terminal EF-Hand Calcium Binding Protein 3 (NECAB3) (AA 179-228) antibodyNECAB3 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-N-Terminal EF-Hand Calcium Binding Protein 3 (NECAB3) (N-Term) antibodyNECAB3 适用: 人, Drosophila melanogaster WB 宿主: 兔 Polyclonal unconjugated
anti-N-Terminal EF-Hand Calcium Binding Protein 3 (NECAB3) (AA 1-362) antibodyNECAB3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-N-Terminal EF-Hand Calcium Binding Protein 3 (NECAB3) (N-Term) antibodyNECAB3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-N-Terminal EF-Hand Calcium Binding Protein 3 (NECAB3) (AA 321-370) antibodyNECAB3 适用: 人, 小鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. protein metabolism by XB51, a novel X11L-binding protein. J. Biol. Chem. 275: 23134-23138, 2000. 2. Sugita, S., Ho, A., Sudhof, T. C. NECABs: a family of neuronal Ca(2+)-binding proteins with an unusual domain structure and a restricted expression pattern. Neuroscience 112: 51-63, 2002. 3. Sumioka, A., Imoto, S., Martins, R. N., Kirino, Y., Suzuki, T. XB51 isoforms mediate Alzheimer's beta-amyloid peptide production by X11L (X11-like protein)-dependent and -independent mechanisms. Biochem. J. 374: 261-268, 2003. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- NECAB3 (N-Terminal EF-Hand Calcium Binding Protein 3 (NECAB3))
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别名
- NECAB3
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背景
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Synonyms: Interleukin-17B, IL-17B, Cytokine CX1, Cytokine-like protein ZCYTO7, Neuronal interleukin-17-related factor, Il17b, Nirf, Zcyto7
Tissue Specificity: Expressed in adult pancreas, small intestine, stomach, spinal cord and testis. Less pronounced expression in prostate, colon mucosal lining, and ovary.
Background: N-terminal EF-hand calcium-binding protein 3 is a protein that in humans is encoded by the NECAB3 gene. The protein encoded by this gene interacts with the amino-terminal domain of the neuron-specific X11-like protein (X11L), inhibits the association of X11L with amyloid precursor protein through a non-competitive mechanism, and abolishes the suppression of beta-amyloid production by X11L. This protein, together with X11L, may play an important role in the regulatory system of amyloid precursor protein metabolism and beta-amyloid generation. The protein is phosphorylated by NIMA-related expressed kinase 2, and localizes to the Golgi apparatus. Multiple transcript variants encoding different isoforms have been found for this gene.
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分子量
- 44 kDa
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基因ID
- 63941
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UniProt
- Q96P71
抗原
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