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NECAB3 抗体 (AA 321-370)

The 兔 多克隆 anti-NECAB3 antibody is suitable to detect NECAB3 in samples from 人 和 小鼠. It has been validated for WB, ELISA, IHC 和 IF.
产品编号 ABIN1534630
发货至: 中国
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Quick Overview for NECAB3 抗体 (AA 321-370) (ABIN1534630)

抗原

See all NECAB3 抗体
NECAB3 (N-Terminal EF-Hand Calcium Binding Protein 3 (NECAB3))

适用

  • 36
  • 30
  • 19
  • 3
  • 2
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  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 35
  • 1
兔

克隆类型

  • 36
多克隆

标记

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  • 1
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  • 1
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  • 1
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This NECAB3 antibody is un-conjugated

应用范围

  • 29
  • 20
  • 11
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  • 6
  • 2
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  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

    • 13
    • 6
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 321-370

    原理

    APBA2BP Antibody

    特异性

    APBA2BP Polyclonal Antibody detects endogenous levels of APBA2BP protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human NECAB3. AA range:321-370

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    NECAB3 (N-Terminal EF-Hand Calcium Binding Protein 3 (NECAB3))

    别名

    NECAB3

    背景

    Synonyms: NECAB3, APBA2BP, NIP1, SYTIP2, XB51, N-terminal EF-hand calcium-binding protein 3, Amyloid beta A4 protein-binding family A member 2-binding protein, Nek2-interacting protein 1, Neuronal calcium-binding protein 3, X11L-binding protein 51

    Background: The protein encoded by this gene interacts with the amino-terminal domain of the neuron-specific X11-like protein (X11L), inhibits the association of X11L with amyloid precursor protein through a non-competitive mechanism, and abolishes the suppression of beta-amyloid production by X11L. This protein, together with X11L, may play an important role in the regulatory system of amyloid precursor protein metabolism and beta-amyloid generation. The protein is phosphorylated by NIMA-related expressed kinase 2, and localizes to the Golgi apparatus. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

    Gene Name: NECAB3

    Protein Name: N-terminal EF-hand calcium-binding protein 3

    分子量

    44 kDa

    基因ID

    63941

    OMIM

    612478

    UniProt

    Q96P71
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