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Clathrin Heavy Chain (CLTC) (AA 967-1668) 抗体

This anti- antibody is a 小鼠 单克隆 antibody detecting in WB, IHC 和 FACS. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7602703
发货至: 中国

Quick Overview for Clathrin Heavy Chain (CLTC) (AA 967-1668) 抗体 (ABIN7602703)

抗原

See all Clathrin Heavy Chain (CLTC) 抗体
Clathrin Heavy Chain (CLTC)

适用

  • 103
  • 68
  • 52
  • 18
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  • 12
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  • 4
  • 4
  • 2
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  • 1
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  • 1
  • 1
  • 1
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  • 1
人, 小鼠, 大鼠

宿主

  • 70
  • 30
  • 5
  • 1
小鼠

克隆类型

  • 64
  • 42
单克隆

标记

  • 41
  • 7
  • 4
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
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  • 2
  • 2
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  • 2
  • 1
  • 1
非结合性

应用范围

  • 70
  • 34
  • 25
  • 20
  • 20
  • 13
  • 13
  • 8
  • 7
  • 5
  • 3
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

克隆位点

6D3
  • 抗原表位

    • 15
    • 12
    • 7
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 967-1668

    原理

    Anti-Clathrin heavy chain/CLTC Antibody Picoband® (monoclonal, 6D3)

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-Clathrin heavy chain/CLTC Antibody Picoband® (monoclonal, 6D3) (ABIN7602703). Tested in Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human Clathrin heavy chain/CLTC recombinant protein (Position: R967-Q1668).

    亚型

    IgG2b
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
    Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    1. Argani, P., Lui, M. Y., Couturier, J., Bouvier, R., Fournet, J.-C., Ladanyi, M. A novel CLTC-TFE3 gene fusion in pediatric renal adenocarcinoma with t(X,17)(p11.2,q23). Oncogene 22: 5374-5378, 2003. 2. Cools, J., Wlodarska, I., Somers, R., Mentens, N., Pedeutour, F., Maes, B., De Wolf-Peeters, C., Pauwels, P., Hagemeijer, A., Marynen, P. Identification of novel fusion partners of ALK, the anaplastic lymphoma kinase, in anaplastic large-cell lymphoma and inflammatory myofibroblastic tumor. Genes Chromosomes Cancer 34: 354-362, 2002. 3. Deborde, S., Perret, E., Gravotta, D., Deora, A., Salvarezza, S., Schreiner, R., Rodriguez-Boulan, E. Clathrin is a key regulator of basolateral polarity. Nature 452: 719-723, 2008.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    Clathrin Heavy Chain (CLTC)

    别名

    CLTC

    背景

    Synonyms: "chromosomal protein, Nonhistone, HMG4 antibody|High mobility group (nonhistone chromosomal) protein 4 antibody|High mobility group box 3 antibody|High mobility group protein 2a antibody|High mobility group protein 4 antibody|High mobility group protein B3 antibody| High mobility group protein HMG4 antibody|HMG 4 antibody|HMG-2a antibody|HMG-4 antibody|HMG2A antibody|HMGB 3 antibody|HMGB3 antibody| HMGB3_HUMAN antibody|MGC90319 antibody|Non histone chromosomal protein antibody|Nonhistone chromosomal protein HMG4 antibody"

    Tissue Specificity: Expressed predominantly in placenta.

    Background: Clathrin heavy chain 1 is a protein that in humans is encoded by the CLTC gene. Clathrin is a major protein component of the cytoplasmic face of intracellular organelles, called coated vesicles and coated pits. These specialized organelles are involved in the intracellular trafficking of receptors and endocytosis of a variety of macromolecules. The basic subunit of the clathrin coat is composed of three heavy chains and three light chains.

    分子量

    180 kDa

    基因ID

    1213

    UniProt

    Q00610
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