UNG 抗体 (AA 96-313)
Quick Overview for UNG 抗体 (AA 96-313) (ABIN7602695)
抗原
See all UNG 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 96-313
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原理
- Anti-UNG Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-UNG Antibody Picoband® (ABIN7602695). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Monkey, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human UNG recombinant protein (Position: E96-L313).
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亚型
- IgG
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anti-Uracil-DNA Glycosylase (UNG) (AA 1-313) antibody
UNG 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Uracil-DNA Glycosylase (UNG) antibodyUNG 适用: 人, 猴 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 1G2 unconjugated
anti-Uracil-DNA Glycosylase (UNG) (AA 1-304) antibodyUNG 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Uracil-DNA Glycosylase (UNG) (AA 114-224) antibodyUNG 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Uracil-DNA Glycosylase (UNG) (Internal Region) antibodyUNG 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Uracil-DNA Glycosylase (UNG) (AA 281-298) antibodyUNG 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Uracil-DNA Glycosylase (UNG) (AA 1-304) antibodyUNG 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Uracil-DNA Glycosylase (UNG) (AA 1-100) antibodyUNG 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Uracil-DNA Glycosylase (UNG) (AA 1-313) antibodyUNG 适用: 人 WB, ELISA, IF, ICC 宿主: 小鼠 Monoclonal k1C12 unconjugated
anti-Uracil-DNA Glycosylase (UNG) (N-Term) antibodyUNG 适用: 人, 小鼠 WB, ELISA, IHC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat, Monkey
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Lindahl T, Ljungquist S, Siegert W, Nyberg B, Sperens B (May 1977). "DNA N-glycosidases: properties of uracil-DNA glycosidase from Escherichia coli". The Journal of Biological Chemistry. 252 (10): 3286-94. 2. Longo MC, Berninger MS, Hartley JL (Sep 1990). "Use of uracil DNA glycosylase to control carry-over contamination in polymerase chain reactions". Gene. 93 (1): 125-8. 3. Pearl LH (Aug 2000). "Structure and function in the uracil-DNA glycosylase superfamily". Mutation Research. 460 (3-4): 165-81. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- UNG (Uracil-DNA Glycosylase (UNG))
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别名
- UNG
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背景
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Synonyms: Phosphatidylethanolamine-binding protein 1, PEBP-1, HCNPpp, Neuropolypeptide h3, Prostatic-binding protein, Raf kinase inhibitor protein, RKIP, Hippocampal cholinergic neurostimulating peptide, HCNP, PEBP1, PBP, PEBP
Tissue Specificity: Expressed in kidney, skeletal muscles, liver, lung, breast, intestine, placenta and skin mainly in epithelial cells (at protein level).
Background: Uracil-DNA glycosylase, also known as UNG or UDG, is a human gene though orthologs exist ubiquitously among prokaryotes and eukaryotes and even in some DNA viruses. The first uracil DNA-glycosylase was isolated from Escherichia coli. This gene encodes one of several uracil-DNA glycosylases. One important function of uracil-DNA glycosylases is to prevent mutagenesis by eliminating uracil from DNA molecules by cleaving the N-glycosylic bond and initiating the base-excision repair (BER) pathway. Uracil bases occur from cytosine deamination or misincorporation of dUMP residues. Alternative promoter usage and splicing of this gene leads to two different isoforms: the mitochondrial UNG1 and the nuclear UNG2. The UNG2 term was used as a previous symbol for the CCNO gene, which has been confused with this gene, in the literature and some databases.
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分子量
- 35 kDa
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基因ID
- 7374
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UniProt
- P13051
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途径
- DNA Damage Repair, Production of Molecular Mediator of Immune Response
抗原
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